International Journal of Hematology

, Volume 109, Issue 2, pp 137–140 | Cite as

JSH practical guidelines for hematological malignancies, 2018: 7. Peripheral T-cell lymphoma (PTCL)

  • Motoko YamaguchiEmail author
  • Ritsuro Suzuki
Guide Line


The 2017 WHO Classification lists approximately 30 disease entities under the category of peripheral T-cell lymphomas (PTCLs) and natural killer (NK) cell neoplasms [1]. The entity-specific prevalence is known to differ between world regions. The International T-Cell Lymphoma Project, a global retrospective study of approximately 1300 patients, found that the most prevalent PTCL entities in western countries, from highest to lowest prevalence, were PTCL not otherwise specified (PTCL-NOS), angioimmunoblastic T-cell lymphoma (AITL), ALK-positive anaplastic large cell lymphoma (ALCL), and ALK-negative ALCL [2]. This chapter covers these four entities. Two other PTCL entities common in Japan, adult T-cell leukemia–lymphoma (ATL) and extranodal NK/T-cell lymphoma, nasal type (ENKL), will be covered in another chapter. Cutaneous T-cell lymphoma (CTCL) is covered in a separate set of guidelines (Evidence-based Guidelines for the Treatment of Malignant Skin Tumors, 2nd Edition) [3].



Copyright information

© Japanese Society of Hematology 2019

Authors and Affiliations

  1. 1.Department of Hematology and OncologyMie University Graduate School of MedicineTsuJapan
  2. 2.Shimane University Hospital Innovative Cancer CenterIzumoJapan

Personalised recommendations