Metal Organic Framework-Molecularly Imprinted Polymer as Adsorbent in Matrix Solid Phase Dispersion for Pyrethroids Residue Extraction from Wheat
Metal organic frameworks-molecular imprinting polymers (MOFs-MIPs) were applied as dispersants of matrix solid phase dispersion (MSPD) followed by gas chromatography-tandem mass spectrometry (GC-MS/MS) to selectively analyze pyrethroids in wheat. MOFs-MIPs characterized by a series of instrumental techniques and the adsorption properties researched by isothermal, kinetics, thermodynamics, and selective binding experiments. The results revealed that the MOFs-MIPs had a larger adsorption capacity (474.56 mg g−1) and fast adsorption time (20 min). What is more, MOFs-MIPs-MSPD procedure clearly increased extraction efficiency and decreased the consumption of organic solvent. The better recoveries of pyrethroids were reached by optimizing MSPD conditions. Under the excellent conditions, the linearity ranges of pyrethroids in wheat samples were obtained varying from 10 to 1000 ng g−1; the limits of detection were in the range of 1.8–2.8 ng g−1 and the precisions were lower than 6.3%. At the same time, the method was successfully applied for detection of three pyrethroids residue in six kinds of wheat samples and cyhalothrin residue detected in one wheat was 23.96 ng g−1, which is lower than the maximum residue limits allowed by the Ministry of Agriculture of the People’s Republic of China. The developed MOFs-MIPs-MSPD-GC-MS/MS method displayed high selectivity, absorbability, simplicity, rapidity, sensitivity, and excellent practical food control applicability.
KeywordsMatrix solid phase dispersion Pyrethroids Metal organic framework Gas chromatography-tandem mass spectrometry Molecularly imprinted polymer Wheat
This study was funded by the Fundamental Research Funds for the Central Universities (No. 2572017EB08), Natural Science Foundation of Heilongjiang Province (JJ2018ZR0081, B20170001), Harbin science and technology innovation talent research special funds (2016RAQXJ151), National Natural Science Foundation of China (NSFC 201401019), Heilongjiang Postdoctoral Fund (LBH-Z16009), and China Postdoctoral Science Foundation (2016M591501, 332017T100218).
Compliance with Ethical Standards
Conflict of Interest
Ting Liang declares that she has no conflict of interest. Shangshu Wang declares that he has no conflict of interest. Ligang Chen declares that he has no conflict of interest. Na Niu declares that she has no conflict of interest.
This article does not contain any studies with human participants or animals performed by any of the authors.
- Asfaram A, Ghaedi M, Dashtian K (2017) Ultrasound assisted combined molecularly imprinted polymer for selective extraction of nicotinamide in human urine and milk samples: spectrophotometric determination and optimization study. Ultrason Sonochem 34:640–650. https://doi.org/10.1016/j.ultsonch.2016.06.018 CrossRefGoogle Scholar
- China Food and Drug Administration (2016) National food safety standards-determination of 475 pesticides and related chemicals residues in grains gas chromatography-mass spectrometry. GB/T 23200.9–2016, pp 1–53Google Scholar
- Ji W, Zhang M, Gao Q, Cui L, Chen L, Wang X (2016) Preparation of hydrophilic molecularly imprinted polymers via bulk polymerization combined with hydrolysis of ester groups for selective recognition of iridoid glycosides. Anal Bioanal Chem 408:5319–5328. https://doi.org/10.1007/s00216-016-9625-6 CrossRefGoogle Scholar
- Li DQ, Zhang X, Kong FF, Qiao XG, Xu ZX (2017a) Molecularly imprinted solid-phase extraction coupled with high-performance liquid chromatography for the determination of trace trichlorfon and monocrotophos residues in fruits. Food Anal Methods 10:1284–1292. https://doi.org/10.1007/s12161-016-0687-z CrossRefGoogle Scholar
- Ministry of Agriculture of the People’s Republic of China (2016) National food safety standard--maximum residue limits for pesticides in food. GB/T 2763-2016, p 125Google Scholar
- Pan XD, Wu PG, Jiang W, Ma BJ (2015) Determination of chloramphenicol, thiamphenicol, and florfenicol in fish muscle by matrix solid-phase dispersion extraction (MSPD) and ultra-high pressure liquid chromatography tandem mass spectrometry. Food Control 52:34–38. https://doi.org/10.1016/j.foodcont.2014.12.019 CrossRefGoogle Scholar
- Qiu H, Gao L, Wang J, Pan J, Yan Y, Zhang X (2017) A precise and efficient detection of seta-cyfluthrin via fluorescent molecularly imprinted polymers with ally fluorescein as functional monomer in agricultural products. Food Chem 217:620–627. https://doi.org/10.1016/j.foodchem.2016.09.028 CrossRefGoogle Scholar
- Uddin R, Iqbal S, Khan M, Parveen Z, Ahmed M, Abbas M (2011) Determination of pesticide residues in rice grain by solvent extraction, column cleanup, and gas chromatography-electron capture detection. Bull Environ Contam Toxicol 86:83–89. https://doi.org/10.1007/s00128-010-0178-7 CrossRefGoogle Scholar
- Wianowska D, Dawidowicz AL (2016) Can matrix solid phase dispersion (MSPD) be more simplified? Application of solventless MSPD sample preparation method for GC-MS and GC-FID analysis of plant essential oil components. Talanta 151:179–182. https://doi.org/10.1016/j.talanta.2016.01.019 CrossRefGoogle Scholar
- Wu Q, Li MN, Huang Z, Shao YM, Bai L, Zhou LC (2018) Well-defined nanostructured core-shell magnetic surface imprinted polymers (Fe3O4@SiO2@MIPs) for effective extraction of trace tetrabromobisphenol A from water. J Ind Eng Chem 60:268–278. https://doi.org/10.1016/j.jiec.2017.11.013 CrossRefGoogle Scholar
- Yin YJ, Pan J, Cao J, Ma Y, Pan G, Wu R, Dai X, Meng M, Yan Y (2016) Rationally designed hybrid molecularly imprinted polymer foam for highly efficient λ-cyhalothrin recognition and uptake via twice imprinting strategy. Chem Eng J 286:485–496. https://doi.org/10.1016/j.cej.2015.10.060 CrossRefGoogle Scholar
- Zhu WJ, Ma W, Li C, Pan J, Dai X, Gan M, Qu Q, Zhang Y (2014) Magnetic molecularly imprinted microspheres via yeast stabilized Pickering emulsion polymerization for selective recognition of lambda-cyhalothrin. Colloids Surf A 453:27–36. https://doi.org/10.1016/j.colsurfa.2014.04.011 CrossRefGoogle Scholar