Non-cystic Sclerosing Polycystic Adenosis: Diagnosis of a Hitherto Undescribed Pattern
A case of sclerosing polycystic adenosis without cysts is described. The lesion occurred as a painless slow growing superficial right parotid lump in a 47 years old woman. The tumor measured 14 × 10 mm and displayed extreme well circumscription, sclerotic stroma with scattered hyaline nodules, sprinkling of mononuclear inflammatory cells and islands of mature fat. The epithelial component was predominantly composed of tubules lined by low columnar to cuboidal epithelium with bland nuclear features. Only focal incomplete acinar differentiation with few cells containing small eosinophilic granules was present. The stroma contained a significant fibromyxoid component with increased cellularity. There was no recurrence on follow-up at 14 months.
KeywordsSclerosing polycystic adenosis Salivary gland Carcinoma
Compliance with Ethical Standards
Conflict of interest
The author has no conflict of interest.
It is author’s institution’s policy not to require formal ethical approval for reports on up to two patients.
- 2.Noonan VL, Kalmar JR, Allen CM, Gallagher GT, Kabani S. Sclerosing polycystic adenosis of minor salivary glands: report of three cases and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007;104(4):516–20. https://doi.org/10.1016/j.tripleo.2006.08.033.CrossRefPubMedGoogle Scholar
- 8.Petersson F, Tan PH, Hwang JS. Sclerosing polycystic adenosis of the parotid gland: report of a bifocal, paucicystic variant with ductal carcinoma in situ and pronounced stromal distortion mimicking invasive carcinoma. Head Neck Pathol. 2011;5(2):188–92. https://doi.org/10.1007/s12105-011-0242-6.CrossRefPubMedPubMedCentralGoogle Scholar