Head and Neck Pathology

, Volume 12, Issue 3, pp 392–406 | Cite as

Ear and Temporal Bone Pathology: Neural, Sclerosing and Myofibroblastic Lesions

  • A. N. Flaman
  • J. K. Wasserman
  • D. H. Gravel
  • B. M. PurginaEmail author
Special Issue: Ear


Neural, sclerosing, and myofibroblastic lesions of the ear and temporal bone present diagnostic challenges for both clinicians and pathologists due to significant overlap in their clinical presentations, histologic appearances, and immunohistochemical profiles. While some of these lesions, such as schwannomas, are relatively common, others are rendered even more difficult because they are encountered very rarely in routine surgical pathology practice. This review is intended to provide an update on the pathology of some of the most commonly encountered primary diagnostic entities for the ear and temporal bone, and includes the following neural lesions: schwannoma, meningioma, and encephalocele/meningocele. Sclerosing lesions that will be discussed include spindle cell and sclerosing rhabdomyosarcoma, sclerosing epithelioid fibrosarcoma, and sclerosing paraganglioma. Finally, myofibroblastic lesions that will be reviewed are nodular fasciitis, IgG4-related disease, and solitary fibrous tumor. For each of these lesions, the differential diagnosis and useful ancillary tests will be discussed in the context of a broad range of additional primary and secondary lesions.


Temporal bone Ear Neurilemmoma Meningioma Encephalocele Rhabdomyosarcoma Solitary fibrous tumor Paraganglioma Fibrosarcoma 


Compliance with Ethical Standards

Conflict of interest

The authors have no conflicts of interest to disclose.

Ethical Approval

This article does not contain any studies with human participants performed by any of the authors.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • A. N. Flaman
    • 1
  • J. K. Wasserman
    • 1
  • D. H. Gravel
    • 1
  • B. M. Purgina
    • 1
    Email author
  1. 1.Division of Anatomical Pathology, Department of Pathology and Laboratory MedicineThe Ottawa Hospital/University of OttawaOttawaCanada

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