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Chemical shift assignments of retinal guanylyl cyclase activating protein 5 (GCAP5)

  • Diana Cudia
  • James B. AmesEmail author
Article
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Abstract

Retinal membrane guanylyl cyclase (RetGC) in photoreceptor rod and cone cells is regulated by a family of guanylyl cyclase activating proteins (GCAP1-7). GCAP5 is expressed in zebrafish photoreceptors and promotes Ca2+-dependent regulation of RetGC enzymatic activity that regulates visual phototransduction. We report NMR chemical shift assignments of the Ca2+-free activator form of GCAP5 (BMRB No. 27705).

Keywords

Retinal guanylyl cyclase RetGC GCAP5 EF-hand Phototransduction 
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Notes

Acknowledgements

We thank Jeff Walton for technical support and help with NMR experiments. Work supported by NIH Grant No. (EY012347) to J.B.A.

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© Springer Nature B.V. 2019

Authors and Affiliations

  1. 1.Department of ChemistryUniversity of CaliforniaDavisUSA

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