The Indian Journal of Pediatrics

, Volume 86, Issue 8, pp 766–767 | Cite as

Cardiac Troponin-T as a Marker of Myocardial Dysfunction in Term Neonates with Perinatal Asphyxia: Correspondence

  • Jorge Luis Alvarado-Socarrás
  • Edgar Fabián Manrique-HernándezEmail author

To the Editor:We have read with interest the paper by Joseph S et al. [1] about Troponin-T in perinatal asphyxia as a marker of myocardial injury. However, it is necessary to discuss aspects related to the real importance of this marker. Perinatal asphyxia can compromise many organs, such as kidney, liver, heart and brain, secondary to ischemic-hypoxic lesions. These lesions will increase ureic nitrogen, creatinine, hepatic and cardiac enzymes, the increase being directly proportional to the severity of the hypoxic injury. The above applies to specific markers of organs such as troponin T, a marker of myocardial damage severity. But the problem can be more serious if there is hemodynamic compromise, such as hypotension (shock), which would increase brain damage. Authors suggest that the increase of the troponin T early, could predict the need of intervention, besides being a prognostic marker. However, certain clinical signs such as bradycardia, capillary filling time, cardiac...


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© Dr. K C Chaudhuri Foundation 2019

Authors and Affiliations

  1. 1.Neonatal UCI Director Fundacion Cardiovascular de ColombiaFloridablancaColombia
  2. 2.Public Health Department, School of MedicineUniversidad Industrial de SantanderBucaramangaColombia

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