Tuberculosis Burden among Household Pediatric Contacts of Adult Tuberculosis Patients: Correspondence
To the Editor: We read with interest the recent article in your journal by Dayal et al.  and found a few issues to ponder upon:
The study looks at prevalence of latent tuberculosis (TB) and TB disease among pediatric household contacts of adult TB. As the data on prevalence among childhood contacts is scarce and there are no established guidelines regarding screening of TB within household pediatric contacts, this study has a rationale. But, it does not add anything new to the existing body of literature, as it is already well known that childhood contacts of adult TB are at risk of latent as well as overt TB diseases .
The study was designed to be cross-sectional but to address the research question of the study one would need a longitudinal design in order to follow up the cases, till the adult index case completes his DOTS therapy . Hence, the study design is inappropriate. Moreover, there is no mention if all the index cases were sputum positive or not.
Category I anti-TB...