The Indian Journal of Pediatrics

, Volume 86, Issue 6, pp 563–564 | Cite as

Effect of Folic Acid Supplementation on Seizure Control in Epileptic Children Receiving Long Term Antiepileptic Therapy: Correspondence

  • Pinky MeenaEmail author
  • Deepika Harit

To the Editor: We read with interest the article by Deopa B et al. studying the effect of folic acid supplementation on seizure control in children receiving long term antiepileptic drugs (AED) [1]. We congratulate the authors for a commendable research. However we have certain doubts regarding the methodology in the manuscript. Firstly, the title and abstract of the study are discrepant. The title seems to be misleading as it fails to project authors’ objective of studying effect of folic acid supplementation only in folate deficient children receiving long term AEDs and not in all children receiving AEDs. Although the authors in their research question want to know whether secondary folate deficiency results in worsening of seizure control in children receiving AEDs; this objective is not addressed in the manuscript.

The methodology in abstract gives impression of an intervention trial between two groups (group A and group B), but later the manuscript reveals presence of a third...


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© Dr. K C Chaudhuri Foundation 2019

Authors and Affiliations

  1. 1.Department of PediatricsUniversity College of Medical Sciences and Guru Teg Bahadur HospitalDelhiIndia

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