The Indian Journal of Pediatrics

, Volume 86, Issue 5, pp 427–432 | Cite as

Assessment of Quality of Life, Anxiety and Depressive Symptoms in Serbian Children with Celiac Disease and their Parents

  • Biljana Stojanović
  • Aleksandar KočovićEmail author
  • Nedeljko Radlović
  • Zoran Leković
  • Dragan Prokić
  • Nela Đonović
  • Stevan Jovanović
  • Biljana Vuletić
Original Article



To evaluate the level of health-related quality of life (QoL) and presence of anxiety and depressive symptoms in Serbian children with celiac disease from the perspective of patients and their parents.


This cross-sectional study investigated the group of children and adolescents with celiac disease aged 5–18 y, and at least one parent of each patient with celiac disease. The patients and their parents were recruited at the Institute of Mother and Child Health of Serbia and the University Children’s Hospital in Belgrade. The instruments used in this study were child-self and parent-proxy versions of the Pediatric Quality of Life Inventory (PedsQL), Screen for Child Anxiety Related Emotional Disorder (SCARED) and Short Mood and Feelings Questionnaire (MFQ). Additional information was collected from the medical records of each patient.


According to the PedsQL questionnaire, the quality of life was similarly assessed by both parents and their children (p > 0.05), as well as the presence of depressive symptoms according to MFQ questionnaire. However, a statistically significant difference was observed in the total score of the SCARED questionnaire for children and parents [total score (p < 0.05), panic-somatic disturbance (p < 0.01) and social anxiety (p < 0.01)].


The patients and their parents in Serbia have similarly assessed the quality of life of children with celiac disease, but the differences in the scores of SCARED questionnaire indicate that it is necessary to include both children and parents in the assessment of QOL.


Celiac disease Children Quality of life Anxiety Depression 


Author Contributions

All authors have contributed equally to the research, statistical processing of results and the writing of this article. Biljana Vuletic will act as guarantor for this paper.

Compliance with Ethical Standards

Conflict of Interest


Source of Funding



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Copyright information

© Dr. K C Chaudhuri Foundation 2019

Authors and Affiliations

  • Biljana Stojanović
    • 1
  • Aleksandar Kočović
    • 2
    Email author
  • Nedeljko Radlović
    • 3
  • Zoran Leković
    • 4
    • 5
  • Dragan Prokić
    • 6
  • Nela Đonović
    • 7
  • Stevan Jovanović
    • 1
  • Biljana Vuletić
    • 8
  1. 1.Higher Education School of Professional Health StudiesBelgradeSerbia
  2. 2.Faculty of Medical Sciences, Department of PharmacyUniversity of KragujevacKragujevacSerbia
  3. 3.Academy of Medical Sciences of the Serbian Medical SocietyBelgradeSerbia
  4. 4.Faculty of Medical SciencesUniversity of BelgradeBelgradeSerbia
  5. 5.University Children HospitalBelgradeSerbia
  6. 6.Mother and Child Health Care Institute of Serbia “Dr Vukan Cupic” BelgradeBelgradeSerbia
  7. 7.Faculty of Medical Sciences, Department of Hygiene and EcologyUniversity of KragujevacKragujevacSerbia
  8. 8.Faculty of Medical Sciences, Department of PediatricsUniversity of KragujevacKragujevacSerbia

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