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Indian Journal of Microbiology

, Volume 59, Issue 4, pp 422–427 | Cite as

Characterization of Skin Microbiome in Tinea Pedis

  • Xiaoping Liu
  • Jingwen Tan
  • Hong Yang
  • Zhiqin Gao
  • Qing Cai
  • Li Meng
  • Lianjuan YangEmail author
Original research article
  • 96 Downloads

Abstract

Tinea pedis has been associated with Trichophyton rubrum infection. However, it’s not clear whether other microbes were implicated in disease pathogenesis. The composition of microbial communities of patients with tinea pedis and healthy controls were analyzed to identify the characteristics of tinea pedis and differences associated with clinical patterns. We found that microbial community structures were different in patients with tinea pedis compared with healthy controls. Moreover, skin microbiome varied in different forms of tinea pedis. Healthy controls exhibited greater fungal diversity than patients with tinea pedis. In patients with tinea pedis, the dominant bacterial and fungal genera were Staphylococcus and Trichophyton. Compared with healthy controls, Corynebacterium tuberculostearicum was decreased and T. rubrum was increased. C. tuberculostearicum was more abundant in vesicular tinea pedis than in hyperkeratotic and interdigital tinea pedis. Interdigital tinea pedis had a higher detection rate of Corynebacterium minutissimum and T. rubrum than the other forms. These results indicated that bacterial microbes may take part in the development of tinea pedis.

Keywords

Tinea pedis Skin microbiome Bacteria Fungi Diversity 

Notes

Acknowledgements

The study was funded by the National Natural Science Foundation of China (81573036) (General program) and National Natural Science Foundation of China (81602744) (Youth program).

Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.

Supplementary material

12088_2019_816_MOESM1_ESM.pdf (8.8 mb)
Supplementary material 1 (PDF 9040 kb)
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Supplementary material 2 (PDF 7241 kb)
12088_2019_816_MOESM3_ESM.pdf (216 kb)
Supplementary material 3 (PDF 216 kb)
12088_2019_816_MOESM4_ESM.pdf (304 kb)
Supplementary material 4 (PDF 303 kb)

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Copyright information

© Association of Microbiologists of India 2019

Authors and Affiliations

  • Xiaoping Liu
    • 1
  • Jingwen Tan
    • 1
  • Hong Yang
    • 1
  • Zhiqin Gao
    • 1
  • Qing Cai
    • 1
  • Li Meng
    • 1
  • Lianjuan Yang
    • 1
    Email author
  1. 1.Department of MycologyShanghai Dermatology HospitalShanghaiPeople’s Republic of China

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