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Otological and Visual Implications of Diabetes Mellitus in North Indian Population

  • Prateek Roy
  • Manish ChandraEmail author
  • Anupam Mishra
  • Veerendra Verma
  • K. K. Sawlani
  • H. P. Singh
  • Sunil Kumar
  • Sandeep Saxena
  • A. B. Singh
  • Shivani Pandey
  • Kauser Usman
  • Pramod Kumar
  • D. Himanshu
Original Article
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Abstract

The worldwide population of diabetic patients is increasing alarmingly with India claiming number one position. It causes irreversible damage to cochlear hair cells, vestibular apparatus, visual pathway, nephrons, nerves, if not checked in time. A total of 188 patients of diabetes mellitus were included in this prospective study. The patients underwent routine anamnesis, hearing handicap inventory and dizziness handicap inventory assessment along with clinical examination for audiological, vestibular, neurological and ophthalmological (fundoscopy) status. In our study a sensorineural hearing loss, retinopathy, neuropathy, vestibulopathy was seen in diabetic patients.

Keywords

Hearing loss Vestibulopathy Retinopathy Nephropathy Diabetes mellitus 

Notes

Acknowledgements

The present manuscript is the thesis work done in the department under the Chief guidance of Prof (Dr.) Anupam Mishra.

Compliance with Ethical Standards

Conflict of interest

All the authors declare that they have no conflict of interest.

References

  1. 1.
    Jordao AMD (1857) Consideration sur un cas du Paris 1857. 11:446Google Scholar
  2. 2.
    Edgar TO (1915) Klinische Untersuchungen uber die Erkrankungen des Gehororgans bei Diabetes Mellitus mit besonderer Berucksichtigung der Erkrankungen des inneren Ohres. Mschr Ohrenheilk Laryngol Rhinol 49:225–260Google Scholar
  3. 3.
    Kakarlapudi V, Sawyer R, Staecker H (2003) The effect of diabetes on sensorineural hearing loss. Otol Neurotol 24(3):382–386CrossRefGoogle Scholar
  4. 4.
    Meena R, Sonkhya D, Sonkhya N (2016) Evaluation of hearing loss in patients with type II diabetes mellitus. Int J Res Med Sci 4(6):2281–2287CrossRefGoogle Scholar
  5. 5.
    Saini S, Saini R, Aseri Y, Singh BK, Verma PC (2014) Sensorineural hearing loss in diabetic patients. Indian J Basic App Med Res 3(3):170–174Google Scholar
  6. 6.
    Manaviat MR, Afkhami M, Shoja MR (2004) Retinopathy and microalbuminuria in type II diabetic patients. BMC Opthalmol 4:9.  https://doi.org/10.1186/1471-2415-4-9 CrossRefGoogle Scholar
  7. 7.
    Sobngwi E, Ndour-Mbaye M, Boateng KA, Ramaiya KL, Njenga EW, Diop SN, Mbanya JC, Ohwovoriole AE (2012) Type 2 diabetes control and complications in specialised diabetes care centres of six sub-Saharan African countries: the Diabcare Africa study. Diabetes Res Clin Pract 95(1):30–36.  https://doi.org/10.1016/j.diabres.2011.10.018Epub 2011 Nov 8 CrossRefPubMedGoogle Scholar
  8. 8.
    Parving HH, Lewis JB, Ravid M, Remuzzi G, Hunsicker LG, DEMAND investigators (2006) Prevalence and risk factor for microalbuminuria in a referred cohort of type II diabetic patients: a global perspective. Kidney Int 69(11):2057–2063CrossRefGoogle Scholar
  9. 9.
    Weng SF, Chen YS, Hsu CJ, Tseng FY (2005) Clinical features of sudden sensorineural hearing loss in diabetic patients. Laryngoscope 115(9):1676–1680CrossRefGoogle Scholar
  10. 10.
    Rajendran S, Anadhalakshmi Mythili B, Vishwanatha R (2011) Evaluation of incidence of sensorineural hearing loss in patients with type II diabetes mellitus. Int J Biol Med Res 2(4):982–987Google Scholar
  11. 11.
    Shafeeq M, Mohammad NA, Somayagi G, Mubeena, Kallikkadan Hebin H (2015) Sensorineural hearing loss in type II diabetes mellitus. IOSR J Dent Med Sci 14(II):56–61Google Scholar
  12. 12.
    Agarwal AC, Pujary K, Ganapathy K, Balakrishnan R, Nayak DR, Hasan F (2013) Pure tone audiometry and otoacoustic emission for the assessment of hearing loss in diabetic patients. Indian J Otol 19:13–17CrossRefGoogle Scholar
  13. 13.
    Tay HL, Ray N, Ohri R (1995) Diabetes mellitus and hearing loss. Clin Otolaryngol 20:130–134CrossRefGoogle Scholar
  14. 14.
    Cullen JR, Cinnamond MJ (1993) Hearing loss in diabetics. J Laryngol Otol 107:179–182CrossRefGoogle Scholar
  15. 15.
    Kurien M, Thomas K, Bhanu TS (1989) Hearing threshold in patients with diabetes mellitus. J Laryngol Otol 103:164–168CrossRefGoogle Scholar
  16. 16.
    Axelsson A et al (1978) Hearing in diabetics. Acta Otolaryngol 356(suppl):3–219Google Scholar
  17. 17.
    Celik O, Yalcin S, Celebi H et al (1996) Hearing loss in Insulin dependant diabetes mellitus. Auris Nasus Larynx 23:127–132CrossRefGoogle Scholar
  18. 18.
    Rigon R, Rossi AG, Cóser PL (2007) Otoneurological findings in type 1 Diabetes mellitus patients. Rev Bras Otorrinolaringol 73(1):106–111CrossRefGoogle Scholar
  19. 19.
    Farooq M, Ahmed A, Mehmood Z, Waheed A (2013) Frequency of sensorineural hearing loss in type 1 and type 2 diabetic patients. Pak J Otolaryngol 29:87–89Google Scholar
  20. 20.
    Mozaffari M, Tajik A, Ariaei N et al (2010) Diabetes mellitus and sensorineural hearing loss among elderly people. East Mediterr Health J 16(9):947–952CrossRefGoogle Scholar
  21. 21.
    Fong DS, Aiello L, Gardner TW, King GL, Blakenship G, Cavallerano JD, Ferris FL 3rd, Klein R (2004) Retinopathy in diabetes. Diabetes Care 27(Suppl 1):S84–S87CrossRefGoogle Scholar
  22. 22.
    Singh Y, Kumari S (2015) The study of correlation between FBS and PPBS in diabetes mellitus and non-diabetes mellitus community of Ajmer, Rajasthan. Int J Basic Appl Med Sci 5(3):35–38. ISSN: 2277-2103 (Online)Google Scholar
  23. 23.
    Akinloye OA, Adaramoye OA, Akinlade KS, Odetola AA, Raji AA (2007) Relationship between fasting plasma glucose and glycated hemoglobin in adult diabetic Nigerians. Afr J Biomed Res 10:127–132Google Scholar
  24. 24.
    Meena RS, Aseri Y, Singh BK, Verma PC (2012) Hearing loss in patients of chronic renal failure: a study of 100 cases. Indian J Otolaryngol Head Neck Surg 64(4):356–359CrossRefGoogle Scholar
  25. 25.
    Klein R, Knudtson MD, Lee KE, Gangnon R, Klein BE (2008) The wisconsin epidemiological study of diabetic retinopathy: the twenty-five-year progression of retinopathy in persons with type 1 diabetes. Opthalmology 115(11):1859–1868CrossRefGoogle Scholar
  26. 26.
    Rema M, Premkumar S, Anitha B, Deepa R, Pradeepa R, Mohan V (2005) Prevalence of diabetic retinopathy in urban India: the Chennai urban rural epidemiology study (CURES) eye study. Investig Opthalmol Vis Sci 46(7):2328–2333CrossRefGoogle Scholar
  27. 27.
    American Diabetes Association (2002) Implications of the United Kingdom prospective diabetes study. Diabetes Care 25(suppl 1):s28–s32Google Scholar
  28. 28.
    Kumari MS, Meghanadh KR, Madhavi J, Jyothi A (2016) Prevalence of otological disorders in diabetic cases with hearing loss. J Diabetes Metab 7:666.  https://doi.org/10.4172/2155-6156.1000666 CrossRefGoogle Scholar
  29. 29.
    Niazi MK, Ameen SS, Saeed K, Yaqub MAM, Khan MD (2011) Retinopathy risk factor among diabetics in a tertiary care military hospital. Pak Armed Force Med J 61(1):38Google Scholar
  30. 30.
    The San Luis Valley Diabetes Study (1989) Methods and prevelance of non insulin dependent diabetes mellitus (NIDDM) in a biethnic Colarado population. Am J Epidemiol 129(2):295–311CrossRefGoogle Scholar
  31. 31.
    Mythili A, Dileep Kumar K, Subrahmanyam KAV, Venkateswarlu K, Buchi RG (2010) Acomparative study of examination scores and quantitative sensory testing in diagnosis of diabetic polyneuropathy. Int J Diabetes Dev Ctries 30(1):43–48CrossRefGoogle Scholar
  32. 32.
    Sumathi K, Prakash M, Menezes GS (2012) Significance of HbA1c in deafness in type 2 diabetes mellitus. J Pharm Biomed Sci 24(24):59–61Google Scholar
  33. 33.
    Sumathi K, Prakash M, Parameaswari PJ, Mary Chandrika A (2016) Significance of hs-CRP in vestibular dysfunction in type II diabetes mellitus. Int J Clin Biochem Res 3(4):392–394Google Scholar
  34. 34.
    Klagenberg FK et al (2013) Vestibular dysfunction in adolescent and young adult after kidney transplant. Int Tinnitus J 18(2):149–155CrossRefGoogle Scholar
  35. 35.
    Gawron W, Pospiech L, Noczynska A, Koziorowska E (2004) Sudden Hearing loss as a first complication of long standing type I diabetes mellitus: a case report. Diabet Med 21(1):96–98CrossRefGoogle Scholar
  36. 36.
    Klagenberg KF, Zeigelboim BS, Jurkiewicz AL, Martins Basetto J (2007) Manifestacoes vestibulococleares em pacientes com diabetes melito tipo I. Rev Bras Otorrinolaringol 73(3):353–358CrossRefGoogle Scholar
  37. 37.
    Agarwal MK, Jha AK, Singh SK (1998) Otorhinological studies in diabetics. Indian J Otolarynogol Head Neck Surg 50(2):116–121CrossRefGoogle Scholar
  38. 38.
    Li J, Zhang T, Shen J, Gong J et al (2008) The changes in vestibular function in patients with diabetes mellitus and its clinical significance. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 22:10–13PubMedGoogle Scholar
  39. 39.
    Erasmus RT, Oyeyinka G, Arijel A (1992) Microalbuminuria in non-insulin-dependent (type2) Nigerian diabetics: relation to glycaemic control, blood pressure and retinopathy. Postgrad Med J 68:638–642CrossRefGoogle Scholar
  40. 40.
    Irshad M, Ishaque M, Mahmood K, Dar UF (2015) Association between sensorineural hearing loss and complicated diabetes mellitus. Pak J Med Health Sci 9(4):1384–1386Google Scholar

Copyright information

© Association of Otolaryngologists of India 2019

Authors and Affiliations

  • Prateek Roy
    • 1
  • Manish Chandra
    • 1
    Email author
  • Anupam Mishra
    • 1
  • Veerendra Verma
    • 1
  • K. K. Sawlani
    • 3
  • H. P. Singh
    • 1
  • Sunil Kumar
    • 1
  • Sandeep Saxena
    • 2
  • A. B. Singh
    • 1
  • Shivani Pandey
    • 4
  • Kauser Usman
    • 3
  • Pramod Kumar
    • 2
  • D. Himanshu
    • 3
  1. 1.Department of ENT Head Neck SurgeryKGMULucknowIndia
  2. 2.Department of OphthalmologyKGMULucknowIndia
  3. 3.Department of MedicineKGMULucknowIndia
  4. 4.Department of BiochemistryKGMULucknowIndia

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