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Isovolumetric Relaxation Time (IVRT): An Effective Tool in Management of Subclinical Hypothyroidism

  • Gaddada Devara Mutt Basavaraj Jyothi Prakash
  • Uttarkar Pandurangarao SantoshEmail author
  • Janarthanan Sridurga
Original Article
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Abstract

Hypothyroidism is a common condition in which thyroid gland doesn’t produce sufficient thyroid hormone. Normal range of TSH is 0.4 to 4 mIU/L. Patients with TSH between 5 and 10 mIU/L, with normal T4 are diagnosed to have subclinical hypothyroidism. Decision to treat, particularly the subclinical hypothyroidism is tailored to individual patients. In our study, isovolumetric relaxation time (IVRT) was used to detect the diastolic function of cardia in hypothyroid patient, with the help of 2D echocardiogram. Normal duration of IVRT is 54 to 65 μs and in hypothyroidism it is expected to increase. To assess, whether IVRT is an effective tool in the management of subclinical hypothyroidism. 50 patients attending otorhinolaryngology OPD with TSH level of 5 to 10 mIU/L were selected for the study. All these were sent for 2D echocardiogram, for the measurement of IVRT. These 50 patients were divided into 2 groups. Group A—patients with TSH level 5 to 10 mIU/L and normal IVRT. Group B—patients with TSH level 5 to 10 mIU/L and prolonged IVRT. Patients in Group A were not given thyroxine, and after 3 months, they were reviewed with TSH level and IVRT duration. Patients in Group B were started with thyroxine, and after 3 months, they were reviewed with TSH level and IVRT duration. The basal and 3 months follow up values of TSH and IVRT was analysed on both the groups. The p value of group A was not significant, but p value group B was significant. IVRT as a measuring tool in sub clinical hypothyroidism will definitely bring a major change in the concepts of treatment.

Keywords

Thyroxine 2D echocardiogram Subclinical hypothyroidism IVRT 

Notes

Compliance with Ethical Standards

Conflict of interest

None.

Ethical Standards

All procedures performed in this study involving human participants were in accordance with the ethical standards of the institutional research committee.

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Copyright information

© Association of Otolaryngologists of India 2019

Authors and Affiliations

  • Gaddada Devara Mutt Basavaraj Jyothi Prakash
    • 1
  • Uttarkar Pandurangarao Santosh
    • 2
    Email author
  • Janarthanan Sridurga
    • 2
  1. 1.Department of Emergency MedicineSS Institute of Medical ScienceDavangereIndia
  2. 2.Department of ENTJJM Medical CollegeDavangereIndia

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