Idiopathic Isolated Nasal Amyloidosis: Report of a Rare Case with Review of Literature
- 2 Downloads
Deposition of amyloid in localized form is rare and most often involves head and neck region. Localized amyloidosis carries good prognosis with surgical debridement offering symptomatic benefit. We present an adolescent male presenting with localized sinonasal amyloidosis managed previously with conservative surgical debridement. The patient was symptomatic from early childhood and the previous histopathological reports were non-specific inflammation. A repeat biopsy revealed features of amyloidosis and retrospective review of past slides revealed the same. On explaining the course of the disease and prognosis, the patient opted for regular follow up. A pertinent comprehensive literature review of the condition is discussed.
KeywordsAmyloidosis Localized Sinonasal Debridement
We thank Dr. Dheeraj Gautam (Department of Pathology, Medanta- The Medicity, Gurugram), for providing us with the pathology slides of the patient.
Compliance with Ethical Standards
Conflict of interest
The authors declare that they have no conflict of interest.
Informed Consent was obtained from the individual participating in the study.
- 2.Prasad D, Somayaji GK, Aroor R, Abdulla MN (2009) Primary nasal amyloidosis. Internet J Otorhinolaryngol 9(2). http://ispub.com/IJORL/9/2/10505
- 5.Cunningham A, Kalwani S, Alsanjari N, Fayad G (2013) Rare subtype of localised nasal amyloidosis. Otorhinolaryngol 6(1):60–63Google Scholar
- 6.Rauba D, Lesinskas E, Petrulionis M, Sukyte D, Valeviciene N, Palionis D (2013) Isolated nasal amyloidosis: a case report. Med Kaunas 49:497–503Google Scholar
- 7.Pearlman AN, Jeffe JS, Zynger DL, Yeldandi AV, Conley DB (2010) Localized amyloidosis of the nasal and paranasal mucosa: a rare pathology. Am J Otolaryngol Head Neck Med Surg 31:130–131Google Scholar