Kimura’s Disease: A Rare Cause of Parotid Swelling

  • M. Muniraju
  • Shruthi DechammaEmail author
Clinical Report


Kimura’s disease also known as subcutaneous angioblastic lymphoid hyperplasia with peripheral eosinophilia is a rare clinicopathological entity. It is a chronic granulomatous disease of unknown etiology. The clinical presentation varies from subcutaneous swellings of the head and neck region with regional lymphadenopathy with salivary gland involvement to systemic manifestations like nephrotic syndrome. The clinical features are mild, rarely life threatening. The present article is a case report of Kimura’s disease presenting as multiple swellings at the left temporal region, left parotid and bilateral post auricular region. Though the lesion is benign, the cosmetic disfigurement caused by the swellings was of significant concern to our patient. MRI Scan was suggestive of a parotid swelling extending into the temporal and post auricular region of the left side. Surgical modality of treatment was adopted- Superficial Parotidectomy with excision of subcutaneous swellings. Histopathological examination confirmed the diagnosis of Kimura’s disease. The mode of presentation as multiple large swellings with the involvement of the parotid gland created a diagnostic dilemma, hence this article intends to consider Kimura’s disease as a rare but possible cause of a parotid swelling.


Kimura’s disease Peripheral eosinophilia Parotid 


  1. 1.
    Li TJ, Chen XM, Wang SZ, Fan MW, Semba I, Kitano M (1996) Kimura’s disease. A clinicopathological study of 54 Chinese patients. Oral Surg Oral Med Oral Pathol 82(5):549–555CrossRefGoogle Scholar
  2. 2.
    Ranka SR, Rajput A, Kantharia CV (2004) Kimura’s disease. Indian J Otorhinolaryngol Head Neck Surg 56(1):43–45Google Scholar
  3. 3.
    Armstrong WB, Allison G, Pena F, Kim JK (1998) Kimura’s disease: two case reports and a literature review. Ann Otol Rhinol Laryngol 107(12):1066–1071CrossRefGoogle Scholar
  4. 4.
    Szporek B, Steplewka K, Cieslik T (2006) Kimura’s disease-case report. Czas Stomatol LIX(10):734–739Google Scholar
  5. 5.
    Abuel-Haija M, Hurford MT (2007) Kimura’s disease. Arch Pathol Lab Med 131(4):650–651PubMedGoogle Scholar
  6. 6.
    Iwai H, Nakae K, Ikeda K et al (2001) Kimura’s disease: diagnosis and prognostic factors. Otorhinolaryngol Head Neck Surg 59(10):1238–1241Google Scholar
  7. 7.
    Osuch-Wójcikiewicz E, Bruzgielewicz A, Lachowska M et al (2014) Kimura’s disease in a Caucasian female; a very rare cause of lymphadenopathy. Case Rep Otolaryngol 2014:415865. CrossRefPubMedPubMedCentralGoogle Scholar
  8. 8.
    Hareyam M, Oouchi A, Nagakura H et al (1998) Radiotherapy for Kimura’s disease: the optimum dosage. Int J Radiat Oncol Biol Phys 40(3):647–651CrossRefGoogle Scholar

Copyright information

© Association of Otolaryngologists of India 2018

Authors and Affiliations

  1. 1.Department of ENT and Head and Neck SurgeryDr. B.R. Ambedkar Medical CollegeBangaloreIndia
  2. 2.BangaloreIndia

Personalised recommendations