A Rare Case of Basal Cell Adenocarcinoma of Parotid Gland with Intracranial Extension

  • Mohamad Norkahfi Razali
  • Marina Mat BakiEmail author
  • Thean Yean Kew
  • Mohd Razif Mohamad Yunus
Clinical Report


Basal cell adenocarcinoma (BCAC) is a rare tumour entity. Despite its tendency to be infiltrative and destructive tumour with propensity to recur, it rarely metastasizes and long-term outcome following surgery is favourable. This paper presents a 42-year-old male with residual BCAC of parotid gland that had extended into infratemporal fossa and intracranial. The important aspect of this case is the rarity occurrence of BCAC of parotid with intracranial extension and its surgical approaches to achieve tumour clearance.


Basal cell adenocarcinoma Parotid tumour Intracranial extension Tumour resection 


Compliance with Ethical Standards

Conflict of interest

Mohamad Norkahfi Razali declares that he has no conflict of interest. Marina Mat Baki declares that she has no conflict of interest. Kew Thean Yean declares that he has no conflict of interest. Mohd Razif Mohamad Yunus declares that he has no conflict of interest.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed Consent

Informed consent was obtained from all individual participants included in the study.


  1. 1.
    Sharma R, Saxena S, Bansal R (2007) Basal cell adenocarcinoma: report of a case affecting the submandibular gland. J Oral Maxillofac Pathol 11:56–59CrossRefGoogle Scholar
  2. 2.
    Barnes L, Eveson JW, Reichart P, Sidransky D (2005) Pathology and genetics of tumours of the head and neck, vol 9., World Health Organization Classification of TumoursIARC Press, Lyon, pp 229–230Google Scholar
  3. 3.
    Farrell T, Chang YL (2007) Basal cell adenocarcinoma of minor salivary glands. Arch Pathol Lab Med 131:1602–1604PubMedGoogle Scholar
  4. 4.
    Ward BK, Seethala RR, Barnes EL, Lai SY (2009) Basal cell adenocarcinoma of a hard palate minor salivary gland: case report and review of the literature. Head Neck Oncol 1:41CrossRefGoogle Scholar
  5. 5.
    Ellis GI, Wischvitch JG (1990) Basal cell adenocarcinomas of the major salivary gland. Oral Surg Oral Med Oral Pathol 69:461–469CrossRefGoogle Scholar
  6. 6.
    Parashar P, Baron E, Papadimitriou J, Ord R, Nikitakis N (2007) Basal cell adenocarcinoma of the oral minor salivary glands: review of the literature and presentation of two cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endodontol 103:77–84CrossRefGoogle Scholar
  7. 7.
    Kudo S, Sawai T, Ikeda K, Watanabe M, Oshima T, Nakabayashi T, Takasaka T (1998) A case of basal cell adenocarcinoma of the parotid gland. Tohoku J Exp Med 186:51–59CrossRefGoogle Scholar
  8. 8.
    Elvey MH, Aghasi M, Wasrbrout Z, Avisar E (2011) Metastasis of parotid basal cell adenocarcinoma to the hand—a case report. Hand 6:321–323CrossRefGoogle Scholar
  9. 9.
    Faquin WC, Powers C (2008) Salivary gland. Cytopathology 268:164–176Google Scholar
  10. 10.
    Franzen A, Koegel K, Knieriem HJ, Pfaltz M (1998) Basal cell adenocarcinoma of the parotid gland: a rare tumor entity: case report and review of the literature. HNO 46:821–825CrossRefGoogle Scholar
  11. 11.
    Wilson JR, Kumar R, van Hille PT (2012) Cerebellopontine angle metastasis of a parotid mucoepidermoid carcinoma arising from perineural invasion along the facial nerve. Br J Neurosurg 26(3):417–419CrossRefGoogle Scholar
  12. 12.
    Hirsch DL, Miles C, Dierks E (2007) Basal cell adenocarcinoma of the parotid gland: report of a case and review of the literature. J Oral Maxillofac Surg 65:2385–2388CrossRefGoogle Scholar

Copyright information

© Association of Otolaryngologists of India 2017

Authors and Affiliations

  • Mohamad Norkahfi Razali
    • 1
  • Marina Mat Baki
    • 1
    Email author
  • Thean Yean Kew
    • 2
  • Mohd Razif Mohamad Yunus
    • 1
  1. 1.Department of Otorhinolaryngology-Head Neck SurgeryUniversiti Kebangsaan Malaysia Medical CentreKuala LumpurMalaysia
  2. 2.Department of RadiologyUniversiti Kebangsaan Malaysia Medical CentreKuala LumpurMalaysia

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