Is there any association between aortic root rotation angle and aortic dissection?
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Thoracic aortic dissection is a probable fatal condition that requires early diagnosis and management. The underlying etiology of this disorder is an important issue that has not been completely responded yet. In the current study, the association between aortic root rotation and ascending aortic dissection has been assessed.
This is a non-randomized retrospective case-control study conducted on twenty-five cases referring with ascending aortic dissection and seventy-five controls that underwent computed tomography (CT) angiography for reasons other than aortic dissection. Aortic root rotation angle and aortic diameter for both cases and controls were measured and then compared.
There was no significant difference regarding age and gender distribution (P value = 0.22 and 0.38 respectively) between patients in case and control groups. The mean values of aortic root rotation angle and aortic diameter in cases were 22.5 ± 10.5° and 43.1 ± 12.5 mm versus 15.7 ± 10.7° and 30.7 ± 5.3 mm in controls (P value = 0.007 and 0.001 respectively). Direct relation was found between aortic root rotation angle and aortic diameter (P value = 0.007, r = 0.276). Mean of aortic root rotation angle was significantly higher in females (P value = 0.02). No association between cases’ age with either aortic root rotation angle or aortic diameter was found (P value = 0.33, r = 0.098, and P value = 0.085, r = 0.173 respectively).
Based on the findings of the current study, aortic root rotation angle was independently in direct association with thoracic aortic dissection. In addition, females had higher aortic root rotation angles.
KeywordsComputed tomography angiography Aortic valve Aortic root
Compliance with ethical standards
The proposal of this study was approved by the Ethics Committee of Isfahan University of Medical Sciences (project number 396830). Informed consent was not used because all CT angiograms had been performed with clinical indication, even though confidentiality reassurance of patient’s information has been given to all patients who undergone CT in our institutes.
Conflict of interest
The authors declare that they have no conflict of interest.
Human and animal rights
There is no objection to animal or human rights in this study.
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