“RFEF” & mitral regurgitation jet direction: surrogate markers for likelihood of left ventricle reverse remodelling in patients with moderate chronic ischemic mitral regurgitation

  • Shiv Kumar ChoudharyEmail author
Inivited Editorial

In this issue of the journal, Siddiqui and colleagues have tried to find an answer to a very important and frequently encountered clinical problem [1].

Ischaemic mitral regurgitation (IMR) is defined as functional mitral regurgitation caused by changes in the myocardium. It is caused by left ventricular (LV) remodelling and dilatation after myocardial infarction [2]. After myocardial infarction, the prevalence of IMR varies from 20 to 50%. The presence of moderate or severe IMR is associated with a 3-fold increased risk of heart failure (HF) and a 1.6-fold increased risk of death at 5 years follow-up. IMR, complicating the patients with coronary artery disease (CAD), is associated with poor long-term outcomes and survival. The management of moderate chronic IMR is still in the grey zone, and further elaboration of this variant is the need of the hour [1].

The proposed mechanism, accepted widely, corresponds to LV remodelling, dilatation and dysfunction leading to geometric changes in...


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Conflict of interest

The author declares no conflict of interest.


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Copyright information

© Indian Association of Cardiovascular-Thoracic Surgeons 2018

Authors and Affiliations

  1. 1.The Department of Cardiothoracic & Vascular SurgeryAll India Institute of Medical ScienceNew DelhiIndia

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