Successful surgical management of combined presence of congenital diaphragmatic hernia, ventricular septal defect, and patent ductus arteriosus in a child with allergy to frusemide—a case report

  • Anand Kumar Mishra
  • Avishek SamaddarEmail author
  • Parag Barwad
  • Ravi Prakash Kanojia
Case report


A 6-week-old male child presented with a right-sided congenital diaphragmatic hernia (CDH), large perimembranous (PM) ventricular septal defect (VSD) and multiple muscular VSDs, and a patent ductus arteriosus (PDA) with severe pulmonary arterial hypertension (PAH). The child was found to be allergic to frusemide. The VSDs were closed, the PDA was ligated, and the CDH was repaired through a right subcostal incision. Postoperatively, there were recurrent episodes of right lung lobar collapse, but the child responded to intravenous antibiotics and nasal continuous positive airway pressure (CPAP). The child is medically stable and on outpatient follow-up. We present this rare combination of diseases in view of a successful simultaneous surgical repair.


Frusemide allergy Combination of VSD Single-stage combined surgical repair 


Compliance with ethical standards

Conflict of interest

There is no conflict of interest among the authors.

Ethical approval

All procedures performed in this case were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from the parents of the child included in the case report.

Written informed consent was also taken from the parents of the child for publication of the case report.


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Copyright information

© Indian Association of Cardiovascular-Thoracic Surgeons 2018

Authors and Affiliations

  1. 1.Department of CTVSPGIMERChandigarhIndia
  2. 2.Department of CardiologyPGIMERChandigarhIndia
  3. 3.Department of Pediatric SurgeryPGIMERChandigarhIndia

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