Five-year clinical outcomes of diabetic patients in the Randomized On/Off Bypass Follow-up (ROOBY-FS) trial—is the evidence enough to change the practice?
- 6 Downloads
The 5-year outcome of diabetic patients undergoing coronary revascularization in the Randomized On/Off Bypass (ROOBY) trial has recently been published . The main finding of the study is that compared to off-pump coronary artery bypass (OPCAB) the 5-year survival is 6.1% higher in diabetics undergoing on-pump coronary artery bypass grafting (CABG). Thus, there is a strong trend toward improved survival with on-pump CABG in diabetics.
The findings of this study have particular relevance in the Indian context where the predominant strategy for coronary artery revascularization is OPCAB  and diabetics constitute almost half of the patients presenting for CABG .
So, based on the report of this trial, is it time to re-evaluate the strategy of coronary revascularization in India? To answer this question, one has to examine not only the results published, but also revisit the trial itself in greater detail.
The ROOBY trial was a controlled, single-blind, randomized trial conducted...
Compliance with ethical standards
Conflict of interest
The author declares that he has no conflict of interest.
- 13.Gaudino M, Benedetto U, Bakaeen F, et al. Off-versus on-pump coronary surgery and the effect of follow-up length and Surgeons' experience: a meta-analysis. J Am Heart Assoc. 2018;7:e010034.Google Scholar
- 15.Puskas JD, Williams WH, Duke PG, et al. Off-pump coronary artery bypass grafting provides complete revascularization with reduced myocardial injury, transfusion requirements, and length of stay: a prospective randomized comparison of two hundred unselected patients undergoing off-pump versus conventional coronary artery bypass grafting. J Thorac Cardiovasc Surg. 2003;125:797–808.CrossRefGoogle Scholar