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Journal of Genetics

, 98:40 | Cite as

Power divergence test statistics for testing Hardy–Weinberg equilibrium

  • Özge KaradagEmail author
Research Note
  • 75 Downloads

Abstract

The Hardy–Weinberg equilibrium (HWE) model states that allele and genotype frequencies in a population will remain constant for generations in the absence of evolutionary effects. A goodness-of-fit test can be used to test if a population is significantly different from the expectations of HWE. Pearson statistics are commonly used in goodness-of-fit tests for testing the HWE. In this paper, a simulation study is carried out to evaluate the performance of power divergence statistics under different sample sizes, effect sizes and minor allele frequencies. A real genotype dataset is also analysed to compare the results of several power divergence test statistics.

Keywords

Hardy–Weinberg equilibrium goodness-of-fit testing genotype distribution power divergence statistics 

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Copyright information

© Indian Academy of Sciences 2019

Authors and Affiliations

  1. 1.Department of StatisticsHacettepe UniversityAnkaraTurkey

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