Journal of Chemical Sciences

, 131:11 | Cite as

Determination of gallic acid using poly(glutamic acid): graphene modified electrode

  • J Jency Feminus
  • R Manikandan
  • S Sriman Narayanan
  • P N DeepaEmail author
Regular Article



Gallic acid (GA) is one of the main phenolic components occurring naturally in plants and has been a subject of increasing interest owing to its antioxidant, anti-mutagenic and anti-carcinogenic properties. The present work describes a rapid and cost-effective analytical procedure for the determination of gallic acid. Poly-Glu/rGO electrode was fabricated by the electro-polymerisation of glutamic acid on reduced graphene oxide (rGO) modified paraffin impregnated graphite electrode (PIGE). The modified electrode was characterized by SEM, AFM and ATR-IR. The electrochemical behavior of gallic acid at the modified sensor was studied by voltammetric and amperometric techniques under optimized conditions in pH 5 acetate buffer. The electrode showed good linear response towards the determination of gallic acid over the range of 0.03–480 \(\upmu {\hbox {M}}\) with 0.01 \(\upmu \hbox {M}\) as the detection limit for voltammetric technique and the amperometric technique showed a linear range of 1–17 \(\upmu \hbox {M}\) with 0.33 \(\upmu \hbox {M}\) as the detection limit. The electrode also showed good stability and reproducibility with a sensitivity of 0.97 \(\upmu \hbox {M}\)/\(\upmu \)A. The proposed method can be applied to detect GA in real samples with satisfactory results.

Graphical abstract

SYNOPSIS This work describes a rapid and cost-effective analytical procedure for the determination of gallic acid. Poly-Glu/rGO electrode was fabricated by electro-polymerisation of glutamic acid on reduced graphene oxide (rGO) modified paraffin impregnated graphite electrode (PIGE). The electrode showed linear response towards gallic acid over the range of 0.03–480 \(\upmu \hbox {M}\) with 0.01 \(\upmu \hbox {M}\) as the detection limit for voltammetric technique and a linear range of 1–17 \(\upmu \hbox {M}\) with 0.33 \(\upmu \hbox {M}\) as the detection limit for amperometric technique. The proposed electrochemical sensor can be applied to detect GA in real samples with satisfactory results.


Poly glutamic acid modified electrode gallic acid and electrochemical sensor 





Poly glutamic acid


Gallic acid



The authors gratefully acknowledge the support of this work by DST-SERB, New Delhi, India.


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Copyright information

© Indian Academy of Sciences 2019

Authors and Affiliations

  • J Jency Feminus
    • 1
  • R Manikandan
    • 1
  • S Sriman Narayanan
    • 1
  • P N Deepa
    • 1
    Email author
  1. 1.Department of Analytical Chemistry, School of Chemical SciencesUniversity of MadrasChennaiIndia

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