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Correction to: Overexpression of Protein Kinase Inhibitor Alpha Reverses Rat Low Voluntary Running Behavior

  • Kolter B. Grigsby
  • Gregory N. Ruegsegger
  • Thomas E. Childs
  • Frank W. Booth
Correction
  • 82 Downloads

Correction to: Mol Neurobiol

  https://doi.org/10.1007/s12035-018-1171-0

The original version of this article unfortunately contained mistake in Table 2 to where two directionality arrows were inverted.
Table 2

Opposite directional changes in various parameters that were measured between low voluntary runners (LVR) and wild-type (WT) groups of rats. Up, horizontal, and down arrows indicate increase, no change, and decrease, respectively. From baseline. (A) Overexpression means rats previously had similar injection dosages of the rat PKIA gene into LVR and WT nucleus accumbens (NAc). Items 2–6 were measured in in tissue punches quickly frozen in liquid nitrogen. (B) Items 7–9 were determined in LVR and WT NAc in response to incubation of their NAc slices with 20 μm of the dopamine receptor 1 agonist SKF-38393, in either non-transfected slices or in those following PKIα overexpression. (* denotes trending directional change)

(A) Wheel-running and molecular response to PKIα overexpression in LVR vs WT rats

Determination

LVR Overexpression

WT Overexpression

  

 1. Voluntary running distance

  

 2. Total PKIα mRNA

  

 3. Endogenous PKIα mRNA

  

 4. NAc Drd1 receptor mRNA

  

 5. NAc Drd2 receptor mRNA

  

 6. NAc Fos mRNA

  

(B) Effect of SKF-38393 on IEG expression: Non-transfected and PKIα overexpression in LVR vs WT rats

Determination

LVR non-transfected

WT non-transfected

LVR overexpression

WT overexpression

 7. NAc Homer1 mRNA

 8. NAc Zif268

↓*

 9. NAc Arc mRNA

With this, the authors hereby publiche the corrected Table 2.

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Kolter B. Grigsby
    • 1
  • Gregory N. Ruegsegger
    • 1
    • 2
  • Thomas E. Childs
    • 1
  • Frank W. Booth
    • 1
    • 3
    • 4
    • 5
  1. 1.Department of Biomedical SciencesUniversity of MissouriColumbiaUSA
  2. 2.Division of Endocrinology, Diabetes and NutritionMayo ClinicRochesterUSA
  3. 3.Department of Nutrition and Exercise PhysiologyUniversity of MissouriColumbiaUSA
  4. 4.Department of PhysiologyUniversity of MissouriColumbiaUSA
  5. 5.Dalton Cardiovascular CenterUniversity of MissouriColumbiaUSA

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