Wollastonite/forsterite composite scaffolds offer better surface for hydroxyapatite formation

  • R Lakshmi
  • Rajan Choudhary
  • Deepalekshmi Ponnamma
  • Kishor Kumar Sadasivuni
  • Sasikumar SwamiappanEmail author


The present work deals with a comparative study of ceramic/ceramic composites for the development of scaffolds for biomedical applications. Wollastonite and forsterite were synthesized by a sol–gel combustion method. The influence of constituents and composition on apatite deposition was studied by fabricating wollastonite/forsterite composites. The X-ray diffraction pattern explains the bone like-apatite deposition within early stages of immersion. The atomic force microscopy micrographs revealed that with an increase in wollastonite content in the composites the roughness was enhanced. Dissolution studies further confirmed the rapid consumption of Ca and P ions from the simulated body fluid. Hence, apatite formation was observed to be more on the surface of a composite containing a higher amount of wollastonite. The results suggest that composites have more influence on the biomineralization activity when compared with pure bioceramics.

Graphical abstract


Wollastonite forsterite composites roughness simulated body fluid apatite 



The authors thank DST-FIST for the XRD, SEM facility and SAIF/IIT Madras for ICP-OES facility. This study was financially supported by Vellore Institute of Technology Research Grants for Engineering, Management and Science (VITRGEMS).


  1. 1.
    Deng J, Li P, Gao C, Feng P, Shuai C and Peng S 2014 Mater. Manuf. Process. 29 877CrossRefGoogle Scholar
  2. 2.
    Sopyan I, Gunawan Shah Q H and Mel M 2016 Manuf. Process. 31 713CrossRefGoogle Scholar
  3. 3.
    Ilyuschenko A, Okovity V A, Shevtsov A I, Kashin N G and Kulak A I 2002 Mater. Manuf. Process. 17 177CrossRefGoogle Scholar
  4. 4.
    Sopyan I, Nawawi N A, Shah Q H, Ramesh S, Tan C Y and Hamdi M 2011 Mater. Manuf. Process. 26 908CrossRefGoogle Scholar
  5. 5.
    Kharaziha M and Fathi M H 2009 Ceram. Int. 35 2449CrossRefGoogle Scholar
  6. 6.
    Ni S and Chang J 2009 J. Biomater. Appl. 24 139CrossRefGoogle Scholar
  7. 7.
    Ni S, Chou L and Chang J 2008 J. Mater. Sci. Mater. Med. 19 359CrossRefGoogle Scholar
  8. 8.
    Dinarvand P, Seyedjafari E, Shafiee A, Jandaghi A B, Doostmohammadi A, Fathi M H et al 2011 ACS Appl. Mater. Interfaces 3 4518CrossRefGoogle Scholar
  9. 9.
    Sebdani M M and Fathi M H 2012 Ceram. Int. 38 1325CrossRefGoogle Scholar
  10. 10.
    Beheri H H, Mohamed K R and El-Bassyouni G T 2013 Mater. Des. 44 461CrossRefGoogle Scholar
  11. 11.
    Lakshmi R and Sasikumar S 2012 Adv. Mater. Res. 584 479CrossRefGoogle Scholar
  12. 12.
    Choudhary R, Manohar P, Vecstaudza J, Yáñez-Gascón M J, Pérez Sánchez H, Nachimuthu R et al 2017 Mater. Sci. Eng. C 77 811CrossRefGoogle Scholar
  13. 13.
    Lin K L, Zhai W Y, Chang J, Zeng Y and Qian W J 2005 Ceram. Int. 31 323CrossRefGoogle Scholar
  14. 14.
    García-Páez I H, Pena P, Baudin C, Rodríguez M A, Cordoba E and De Aza A H 2016 Bol. Soc. Esp. Ceram. V. 55 1CrossRefGoogle Scholar
  15. 15.
    Choudhary R, Vecstaudza J, Krishnamurithy G, Balaji Raghavendran H R, Murali M R, Kamarul T et al 2016 Mater. Sci. Eng. C 68 89CrossRefGoogle Scholar
  16. 16.
    Vallet-Regi M, Salinas A J, Roman J and Gil M 1999 J. Mater. Chem. 9 515CrossRefGoogle Scholar
  17. 17.
    Liu X, Ding C and Chu P K 2004 Biomaterials 25 1755CrossRefGoogle Scholar
  18. 18.
    Kim H M, Himeno T, Kokubo T and Nakamura T 2005 Biomaterials 26 4366CrossRefGoogle Scholar
  19. 19.
    Hou X, Yin G, Chen X, Liao X, Yao Y and Huang Z 2011 Appl. Surf. Sci. 257 3417CrossRefGoogle Scholar

Copyright information

© Indian Academy of Sciences 2019

Authors and Affiliations

  1. 1.Department of ChemistryAuxilium CollegeVelloreIndia
  2. 2.Division of Chemistry, Department of Science and Humanities, Saveetha School of EngineeringSaveetha Institute of Medical and Technical Sciences (SIMATS)ChennaiIndia
  3. 3.Center for Advanced MaterialsQatar UniversityDohaQatar
  4. 4.Department of Mechanical and Industrial EngineeringQatar UniversityDohaQatar
  5. 5.Department of Chemistry, School of Advanced SciencesVellore Institute of TechnologyVelloreIndia

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