Journal of Gastrointestinal Cancer

, Volume 50, Issue 4, pp 1009–1013 | Cite as

Recurrent Pancreatitis Secondary to Diffuse Large B Cell Lymphoma

  • Maham HayatEmail author
  • Taseen A. Syed
  • Molly Disbrow
  • Ngoc Thy Bao Tran
  • Zain Ul Abideen Asad
  • William M. Tierney
Case Report


Pancreatic lymphoma is an extremely rare pancreatic tumor representing less than 0.5% of pancreatic tumors, with diffuse large B cell lymphoma (DLBCL) being the predominant type. Pancreatic involvement by B cell lymphoma has been reported in the literature; however, acute pancreatitis is a very uncommon presentation. Here, we report a case of secondary pancreatic involvement of DLBCL presenting as pancreatitis, which underscores the importance of defining the cause of unexplained recurrent pancreatitis.

Case Presentation

A 57-year-old female with a history of thyrotoxicosis and recent admissions for pancreatitis presented with a 5-day history of severe, sudden-onset, upper abdominal pain radiating to the back. Upon admission, the patient was hemodynamically stable and afebrile, with a blood pressure of 139/70 mmHg, heart rate of 89 beats per minute, and respiratory rate of 12 per minute. Physical exam was remarkable for abdominal distension, epigastric, and left upper...



Sandra J. Admire BS MT (ASCP), Lead Clinical Laboratory Scientist, OUMC Flow Cytometry Laboratory.

Author’s Contributions

Maham Hayat M.D., case report drafting and discussion writing; Taseen A. Syed M.D., case report writing, literature review, and discussion writing; Molly Disbrow M.D., case report writing and finalizing the manuscript; Ngoc Thy Bao Tran M.D., image selection; Zain Asad M.D., literature review; William M. Tierney M.D., critical revision of the article and final approval of the manuscript. All authors reviewed the final manuscript before submission.

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.

Informed Consent

Informed patient consent was obtained for case publication.

Article Guarantor

William M. Tierney M.D.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Internal MedicineUniversity of Oklahoma Health Sciences CenterOklahoma CityUSA
  2. 2.Section of Digestive Diseases and NutritionUniversity of Oklahoma Health Sciences CenterOklahoma CityUSA
  3. 3.Department of PathologyUniversity of Oklahoma Health Sciences CenterOklahoma CityUSA
  4. 4.Department of CardiologyUniversity of Oklahoma Health Sciences CenterOklahoma CityUSA

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