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Journal of Gastrointestinal Cancer

, Volume 50, Issue 4, pp 962–966 | Cite as

Extramedullary Plasmacytoma of the Pancreas Complicated with Left-Sided Portal Hypertension—a Case Report and Literature Review

  • Ján CsomorEmail author
  • Bohuš Bunganič
  • Dominika Dvořáková
  • Petr Hříbek
  • Klára Kmochová
  • Vít Campr
  • Inna Tučková
  • Cyril Šálek
  • Petr Urbánek
  • Miroslav Zavoral
Case Report

Introduction

Plasma cell neoplasms (PCNs) are clonal diseases of terminally differentiated B cells, which secrete a typical monoclonal immunoglobulin called M-protein or paraprotein. They account for approximately 1% of malignant and 10–15% of hematopoietic tumors [1]. PCN can occur as a single lesion (so-called solitary plasmacytoma) or as a multiple lesion (multiple myeloma). Solitary plasmacytomas account for only about 5% of PCNs and present mostly as a single bone lesion (solitary bone plasmacytoma), less commonly as a soft tissue mass (primary extramedullary plasmacytoma (EMP)) [2, 3]. EMPs therefore represent approximately 3% of all PCNs [4].

Almost 80–90% of extramedullary plasmacytomas occur in the head or neck, primarily in the upper respiratory tract. Less than 10% of EMPs affect the gastrointestinal tract (mostly the liver and the stomach) [4, 5]. It is very rare for a plasmacytoma to affect the pancreas: they account for fewer than 0.1% of all pancreatic tumors....

Notes

Compliance with Ethical Standards

Conflict of Interest

The authors declare that there are no conflicts of interest.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Ján Csomor
    • 1
    Email author
  • Bohuš Bunganič
    • 1
  • Dominika Dvořáková
    • 1
  • Petr Hříbek
    • 1
  • Klára Kmochová
    • 1
  • Vít Campr
    • 2
  • Inna Tučková
    • 3
  • Cyril Šálek
    • 4
  • Petr Urbánek
    • 1
  • Miroslav Zavoral
    • 1
  1. 1.Department of Internal Medicine1st Medical Faculty Charles University and Central Military Hospital PraguePragueCzech Republic
  2. 2.Department of Pathology and Molecular Medicine, 2nd Faculty of MedicineCharles University in Prague and Motol University HospitalPragueCzech Republic
  3. 3.Department of PathologyCentral Military Hospital PraguePragueCzech Republic
  4. 4.Institute of Hematology and Blood TransfusionPragueCzech Republic

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