Extramedullary Plasmacytoma of the Pancreas Complicated with Left-Sided Portal Hypertension—a Case Report and Literature Review
- 69 Downloads
Plasma cell neoplasms (PCNs) are clonal diseases of terminally differentiated B cells, which secrete a typical monoclonal immunoglobulin called M-protein or paraprotein. They account for approximately 1% of malignant and 10–15% of hematopoietic tumors . PCN can occur as a single lesion (so-called solitary plasmacytoma) or as a multiple lesion (multiple myeloma). Solitary plasmacytomas account for only about 5% of PCNs and present mostly as a single bone lesion (solitary bone plasmacytoma), less commonly as a soft tissue mass (primary extramedullary plasmacytoma (EMP)) [2, 3]. EMPs therefore represent approximately 3% of all PCNs .
Almost 80–90% of extramedullary plasmacytomas occur in the head or neck, primarily in the upper respiratory tract. Less than 10% of EMPs affect the gastrointestinal tract (mostly the liver and the stomach) [4, 5]. It is very rare for a plasmacytoma to affect the pancreas: they account for fewer than 0.1% of all pancreatic tumors....
Compliance with Ethical Standards
Conflict of Interest
The authors declare that there are no conflicts of interest.
- 6.Guidelines on the diagnosis and management of solitary plasmacytoma of bone, extramedullary plasmacytoma and multiple solitary plasmacytomas. http://www.bcshguidelines.com/ 4_HAEMATOLOGY_GUIDELINES.html?dpage=3&dtype=Haematoncology&sspage=0&ipage=0#gl.
- 16.Sugimoto M, Takagi T, Hikichi T, Suzuki R, Watanabe K, Nakamura J, et al. Conventional versus contrast-enhanced harmonic endoscopic ultrasonography-guided fine-needle aspiration for diagnosis of solid pancreatic lesions: a prospective randomized trial. Pancreatology. 2015;15(5):538–41.CrossRefGoogle Scholar