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Tracheostomy After Severe Acute Brain Injury: Trends and Variability in the USA

  • Vijay KrishnamoorthyEmail author
  • Catherine L. Hough
  • Monica S. Vavilala
  • Jordan Komisarow
  • Nophanan Chaikittisilpa
  • Abhijit V. Lele
  • Karthik Raghunathan
  • Claire J. Creutzfeldt
Original Work

Abstract

Background/Objective

Severe acute brain injury (SABI) is responsible for 12 million deaths annually, prolonged disability in survivors, and substantial resource utilization. Little guidance exists regarding indication or optimal timing of tracheostomy after SABI. Our aims were to determine national trends in tracheostomy utilization among mechanically ventilated patients with SABI in the USA, as well as to examine factors associated with tracheostomy utilization following SABI.

Methods

We conducted a population-based retrospective cohort study using the National Inpatient Sample from 2002 to 2011. We identified adult patients with SABI, defined as a primary diagnosis of stroke, traumatic brain injury or post-cardiac arrest who received mechanical ventilation for greater than 96 h. We analyzed trends in tracheostomy utilization over time and used multilevel mixed-effects logistic regression to analyze factors associated with tracheostomy utilization.

Results

There were 94,082 hospitalizations for SABI during the study period, with 30,455 (32%) resulting in tracheostomy utilization. The proportion of patients with SABI who received a tracheostomy increased during the study period, from 28.0% in 2002 to 32.1% in 2011 (p < 0.001). Variation in tracheostomy utilization was noted based on patient and facility characteristics, including higher odds of tracheostomy in large hospitals (OR 1.34, 95% CI 1.18–1.53, p < 0.001, compared to small hospitals), teaching hospitals (OR 1.15, 95% CI 1.06–1.25, p = 0.001, compared to non-teaching hospitals), and urban hospitals (OR 1.60, 95% CI 1.33–1.92, p < 0.001, compared to rural hospitals).

Conclusions

Tracheostomy utilization has increased in the USA among patients with SABI, with wide variation by patient and facility-level factors.

Keywords

Brain injury Tracheostomy Respiratory failure 

Notes

Author Contribution

All authors have given final approval of the published work. VK contributed to the conception and design of the work, analysis, interpretation, and drafting the manuscript. CLH, MSV, JK, AVL, KR, CJC contributed to the conception and design of the work, interpretation, and drafting the manuscript. NC contributed to the analysis, interpretation, and drafting the manuscript.

Source of support

NIH L30 NS084420 (Krishnamoorthy), K23 NS099421 (Creutzfeldt).

Conflicts of Interest

None

Supplementary material

12028_2019_697_MOESM1_ESM.docx (19 kb)
Supplementary material 1 (DOCX 19 kb)

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature and Neurocritical Care Society 2019

Authors and Affiliations

  • Vijay Krishnamoorthy
    • 1
    • 4
    Email author
  • Catherine L. Hough
    • 2
    • 4
  • Monica S. Vavilala
    • 3
    • 4
  • Jordan Komisarow
    • 5
  • Nophanan Chaikittisilpa
    • 4
  • Abhijit V. Lele
    • 3
    • 4
  • Karthik Raghunathan
    • 1
  • Claire J. Creutzfeldt
    • 6
  1. 1.Department of AnesthesiologyDuke UniversityDurhamUSA
  2. 2.Department of Medicine, Division of Pulmonary and Critical Care MedicineUniversity of WashingtonSeattleUSA
  3. 3.Department of Anesthesiology and Pain MedicineUniversity of WashingtonSeattleUSA
  4. 4.Harborview Injury Prevention and Research Center, University of WashingtonSeattleUSA
  5. 5.Department of NeurosurgeryDuke UniversityDurhamUSA
  6. 6.Department of NeurologyUniversity of WashingtonSeattleUSA

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