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Endocrine

, Volume 65, Issue 3, pp 707–709 | Cite as

Uremic leontiasis ossea

  • Weverton M. LuchiEmail author
  • Júlia Guasti P. Vianna
  • Lucas Enock V. Roberto
  • Edgard Augusto Villas Boas
  • Everlayny F. Costalonga
Endocrine Imaging
A 36-year-old man with chronic kidney disease (CKD), undergoing hemodialysis therapy since 16-year-old, was referred to our hospital for the management of renal osteodystrophy. Fifteen years ago, he began to develop progressive painful changes in his body and face (Fig. 1a, b), especially massive enlargement of the jaws and palate (Fig. 1d, e). Substantial thoracic cage deformities resembling “pigeon chest” appearance (Fig. 1c), loss of height (171 to 160 cm), and shortening and clubbing of the distal phalanges were observed (Fig. 1f). Previous history also included chronic fistulized osteomyelitis of the left jaw, which appeared 5 years ago after a tooth extraction procedure, and fractures in the right clavicle and bilateral femur fractures, requiring the use of crutches to walk. Blood test results on admission showed total calcium level 9.2 mg/dL, phosphorus 8.3 mg/dL, 25-hydroxy-vitamin D of 27 ng/mL, alkaline phosphatase 3534 IU/L (normal range, 40–150 IU/L), and intact...

Notes

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Informed consent

Informed consent was obtained from the patient to publish this report.

References

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    V.S. Lee et al. Uremic leontiasis ossea: “bighead” disease in humans? Radiologic, clinical, and pathologic features. Radiology 199(1), 233–240 (1996)CrossRefGoogle Scholar
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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Nephrology Service, Cassiano Antonio Moraes University HospitalFederal University of Espírito Santo (HUCAM-UFES)VitóriaBrazil
  2. 2.Medical Resident in Internal Medicine at Cassiano Antonio Moraes HospitalFederal University of Espírito Santo (HUCAM-UFES)VitóriaBrazil
  3. 3.Graduating Medical Student of Federal University of Espírito SantoVitóriaBrazil
  4. 4.Department of Clinical Medicine, Division of EndocrinologyFederal University of Espírito SantoVitóriaBrazil

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