Stem Cell Reviews and Reports

, Volume 15, Issue 4, pp 506–518 | Cite as

Is Stem Cell Commerce in Small Animal Therapies Scientifically and Morally Justified?

  • Luane Lopes PinheiroEmail author
  • Ana Rita de Lima
  • Érika Branco


The lack of clear regulations for the use of veterinary stem cells has triggered the commercialization of unproven experimental therapies for companion animal diseases. Adult stem cells have complex biological characteristics that are directly related to the therapeutic application, but several questions remain to be answered. In order to regulate the use of these cells, well-conducted, controlled scientific studies that generate high-quality data should be performed, in order to assess the efficacy and safety of the intended treatment. This paper discusses the scientific challenges of mesenchymal stem cell therapy in veterinary regenerative medicine, and reviews published trials of adipose-tissue-derived stem cells in companion animal diseases that spontaneously occur.


Adipose-derived stem cell (ASC) Cat Cell therapy Dog Small animal 



This work was supported in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), Brasil (Finance Code 001).

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.


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© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Institute of Animal Health and ProductionFederal Rural University of AmazôniaBelémBrazil

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