Interactions Between Different Selenium Compounds and Essential Trace Elements Involved in the Antioxidant System of Laying Hens
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The purpose of this study was to investigate the interactions between different selenium (Se) compounds including sodium selenite (SS), selenium-enriched yeast (SY), and nano-selenium (NS) and various essential trace elements involved in the antioxidant systems, and to evaluate the effects on laying performance and egg quality. A total of 288 21-week-old Hyline Sophie hens were allotted to four dietary treatments: (1) basal diet without Se supplementation; (2) basal diet supplemented with 0.3 mg/kg Se of SS; (3) basal diet supplemented with 0.3 mg/kg Se of SY; (4) basal diet supplemented with 0.3 mg/kg Se of NS. Each treatment had eight replicates with nine hens per replicate. The trial lasted for 35 days. Results demonstrated that NS supplementation decreased the egg production (EP) and increased the feed conversion rate (FCR) and eggshell thickness and that SY changed the egg shape index (p < 0.05). Supplementation with three Se compounds significantly increased serum Se concentration and glutathione peroxidase (GSH-Px) activity in all treatment groups, as well as total superoxide dismutase (T-SOD) activity in the SY and NS groups. Yolk iron (Fe) and copper (Cu) concentrations in the NS group were also increased with Se supplementation. While the serum zinc (Zn) concentration decreased in the NS and SY groups, as well as the yolk manganese (Mn) concentration in the SY group. And the total antioxidant capability (T-AOC) of yolk with 3 days of storage in the SY and NS groups, malondialdehyde (MDA) value in the NS group, and the T-SOD activity and MDA value of yolk with 10 days of storage in the SY group also decreased. Thus, the source of Se compounds may influence the balance between Se and other trace elements including Zn, Mn, Fe, and Cu, which is important for proper antioxidant defense in blood and egg yolk of laying hens.
KeywordsAntioxidant system Selenium Trace elements Laying hens
Yurong Zhao and Jiahua He designed the experiment; Xue Lin analyzed the data; and Xue Lin, Ting Yang, and Yinli Ji performed the experiments. Xue Lin wrote the manuscript, and Yurong Zhao, Jianhua He, and Hua Li revised it. Xue Lin, Ting Yang, and Yinli Ji contributed to data collection and analysis. All authors read and approved the final manuscript.
This research received support from the Qingyuan Technology Program (2018B02) and Guangzhou Tanke Bio-tech Co., Ltd., Guangdong, China.
Compliance with Ethical Standards
Experiments were carried out in accordance with the ethical guidelines of Hunan Agricultural University for the care and use of laboratory animals.
The authors declare that they have no conflict of interest.
- 1.López-Alonso M (2012) Trace minerals and livestock: not too much not too little. ISRN Vet Sci 2012:1–18. https://doi.org/10.5402/2012/704825
- 2.Chantiratikul A, Chinrasri O, Chantiratikul P (2018) Effect of selenium from selenium-enriched kale sprout versus other selenium sources on productivity and selenium concentrations in egg and tissue of laying hens. Biol Trace Elem Res 182(1):1–6. https://doi.org/10.1007/s12011-017-1069-0 CrossRefGoogle Scholar
- 4.Placha I, Takacova J, Ryzner M, Cobanova K, Laukova A, Strompfova V, Venglovska K, Faix S (2014) Effect of thyme essential oil and selenium on intestine integrity and antioxidant status of broilers. Br Poult Sci 55(1):105–114 https://www.tandfonline.com/doi/abs/10.1080/00071668.2013.873772 CrossRefGoogle Scholar
- 6.Li, S., Gao, F., Huang, J., Wu, Y., Wu, S., & Lei, X. G. (2018). Regulation and function of avian selenogenome. Biochim Biophys Acta Gen Subj, S0304416518300916. https://doi.org/10.1016/j.bbagen.2018.03.029
- 8.Huang, J. Q., Zhou, J. C., Wu, Y. Y., Ren, F. Z., & Lei, X. G (2018) Role of glutathione peroxidase 1 in glucose and lipid metabolism-related diseases. Free Radic Biol Med, 127, S0891584918309109-. https://doi.org/10.1016/j.freeradbiomed.2018.05.077, 108, 115
- 12.Boostani A, Sadeghi AA, Mousavi SN, Chamani M, Kashan N (2015) The effects of organic, inorganic, and nano-selenium on blood attributes in broiler chickens exposed to oxidative stress. Acta Sci Vet, 43(1). http://bepls.com/sep_2014/25.pdf
- 21.Sirirat N, Lu JJ, Hung Alex TY, Chen SY, Tu FL (2012) Effects different levels of nanoparticles chromium picolinate supplementation on growth performance, mineral retention, and immune responses in broiler chickens. J Agric Sci (1916-9752), 4(12). https://doi.org/10.5539/jas.v4n12p48
- 23.Lin X, Liu Y, Meng T, Xie C, Wu X, Yin Y (2018) Circadian calcium feeding regime in laying hens related to zinc concentration, gene expression of circadian clock, calcium transporters and oxidative status[J]. J Trace Elem Med Biol 50:518–526. https://doi.org/10.1016/j.jtemb.2018.03.002 CrossRefGoogle Scholar
- 25.Jia R, Ma Q, Fan Y, Ji C, Zhang J, Liu T et al (2016) The toxic effects of combined aflatoxins and zearalenone in naturally contaminated diets on laying performance, egg quality and mycotoxins residues in eggs of layers and the protective effect of bacillus subtilis biodegradation product. Food Chem Toxicol 90:142–150. https://doi.org/10.1016/j.fct.2016.02.010
- 29.Chen F, Zhu L, Qiu H, Qin S (2017) Selenium-enriched Saccharomyces cerevisiae improves growth, antioxidant status and selenoprotein gene expression in arbor acres broilers. J Anim Physiol Anim Nutr (Berl) 101(2):259–266. https://doi.org/10.1111/jpn.12571
- 30.Pappas AC, Zoidis E, Georgiou CA, Demiris N, Surai PF, Fegeros K (2011) Influence of organic selenium supplementation on the accumulation of toxic and essential trace elements involved in the antioxidant system of chicken. Food Addit Contam Part A 28(4):446–454. https://doi.org/10.1080/19440049.2010.549152 CrossRefGoogle Scholar
- 31.Chantiratikul A, Chinrasri O, Chantiratikul P (2008) Effect of sodium selenite and zinc-l-selenomethionine on performance and selenium concentrations in eggs of laying hens. Asian Australas J Anim Sci 21(7):1048–1052. https://doi.org/10.5713/ajas.2008.70576
- 40.Yao H, Zhao X, Fan R, Sattar H, Zhao J, Zhao W et al (2017) Selenium deficiency-induced alterations in ion profiles in chicken muscle. Plos One 12(9):e0184186. https://doi.org/10.1371/journal.pone.0184186
- 41.Zheng SF, Xing HJ, Zhang QJ, Xue H, Zhu FT, Xu SW (2018) Pharmacokinetics of sodium selenite administered orally in blood and tissues of selenium-deficient ducklings. Biol Trace Elem Res. https://doi.org/10.1007/s12011-018-1567-8
- 42.Jin, X., Jia, T., Liu, R., & Xu, S. (2018). The antagonistic effect of selenium on cadmium-induced apoptosis via ppar-γ/pi3k/akt pathway in chicken pancreas. J Hazard Mater, S0304389418304412-. https://doi.org/10.1016/j.jhazmat.2018.06.003
- 43.Gao T, Wang F, Li S, Luo X, Zhang K (2011) Manganese regulates manganese-containing superoxide dismutase (mnsod) expression in the primary broiler myocardial cells. Biol Trace Elem Res 144(1–3):695–704. https://doi.org/10.1007/s12011-011-9093-y
- 44.Feng J, Ma WQ, Xu ZR, He JX, Wang YZ, Liu JX (2009) The effect of iron glycine chelate on tissue mineral levels, fecal mineral concentration, and liver antioxidant enzyme activity in weanling pigs. Anim Feed Sci Technol 150(1):106–113. https://doi.org/10.1016/j.anifeedsci.2008.07.004
- 45.Zhang Y, Wan D, Zhou X, Long C, Wu X, Li L, He L, Huang P, Chen S, Tan B, Yin Y (2017) Diurnal variations in iron concentrations and expression of genes involved in iron absorption and metabolism in pigs. Biochem Biophys Res Commun 490(4):1210–1214. https://doi.org/10.1016/j.bbrc.2017.06.187
- 46.Soares MP, Hamza I (2016) Macrophages and iron metabolism. Immunity 44(3):492–504. https://doi.org/10.1016/j.immuni.2016.02.016
- 48.Rao SVR, Prakash B, Panda AK, Poonam S, Murthy OK (2013) Effect of supplementing organic selenium on performance, carcass traits, oxidative parameters and immune responses in commercial broiler chickens. Asian Australas J Anim Sci 26(2):247–252. https://doi.org/10.5713/ajas.2012.12299 CrossRefGoogle Scholar
- 50.Meng TT, Liu YL, Xie CY, Zhang B, Huang YQ, Zhang YW et al (2018) Effects of different selenium sources on laying performance, egg selenium concentration, and antioxidant capacity in laying hens. Biol Trace Elem Res. https://doi.org/10.1007/s12011-018-1490-z