Clinical Applications of Echo Strain Imaging: a Current Appraisal

  • Agostina M. Fava
  • Dane Meredith
  • Milind Y. DesaiEmail author
Imaging (Q Truong, Section Editor)
Part of the following topical collections:
  1. Topical Collection on Imaging


Purpose of review

This article reviews recent advances in echocardiographic strain imaging, particularly in its ability to prognosticate in cardiovascular outcomes and impact clinical decision making.

Recent findings

Strain has been proposed as a sensitive tool in detecting early ventricular dysfunction. Left ventricular global longitudinal strain (LV-GLS) detects subtle changes in myocardial function, often not quantifiable by ejection fraction alone. Thus, LV-GLS provides the opportunity for early decision-making, and the implementation of more effective treatments, improving outcomes in a variety of diseases such as valvular heart diseases, cardio-oncology, ischemic heart disease, cardiomyopathies, heart transplantation, and pericardial diseases and cardiomyopathies.


Strain is a promising tool for the early detection of myocardial dysfunction in patients with preserved left ventricular ejection fraction and can prognosticate long-term outcomes.


Strain Speckle-tracking global longitudinal strain Left ventricular deformation Cardiovascular outcomes 



Dr. Desai acknowledges Haslam family endowed chair in cardiovascular medicine.

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflicts of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

References and Recommended Reading

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Agostina M. Fava
    • 1
  • Dane Meredith
    • 1
  • Milind Y. Desai
    • 1
    Email author
  1. 1.Heart and Vascular InstituteCleveland ClinicClevelandUSA

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