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Current Urology Reports

, 20:47 | Cite as

First- and Second-Generation Temporary Implantable Nitinol Devices As Minimally Invasive Treatments for BPH-Related LUTS: Systematic Review of the Literature

  • Daniele Amparore
  • Sabrina De Cillis
  • Gabriele Volpi
  • Enrico Checcucci
  • Matteo Manfredi
  • Ivano Morra
  • Michele Di Dio
  • Cristian Fiori
  • Francesco PorpigliaEmail author
  • on behalf of ESUT Group
BENIGN PROSTATIC HYPERPLASIA (K MCVARY, SECTION EDITOR)
Part of the following topical collections:
  1. Topical Collection on Benign Prostatic Hyperplasia

Abstract

Introduction

In the last decade, there has been a growing interest in minimally invasive treatment for benign prostatic hyperplasia (BPH) associated with lower urinary tract symptoms (LUTS). In this field, one of the options currently available is the temporary implantable nitinol device (iTIND) (Medi-Tate®; Medi-Tate Ltd., Or Akiva, Israel).

Purpose of the Work

To review the recent data available in the literature regarding the role of the first-generation (TIND) and second-generation (iTIND) devices for the management of BPH with LUTS, especially focusing on follow-up of functional outcomes.

Evidence Acquisition

PubMed, Embase, and the Cochrane Central Register of Controlled Trials were screened for clinical trials on this topic.

Evidence Synthesis

Literature evidences regarding implantation of TIND and iTIND for PBH with LUTS are limited. There are only three studies available, one with a medium-term follow-up. The results of these studies suggested that both the TIND and iTIND implantations are safe, effective, and well-tolerated procedures, allowing spare ejaculation in sexually active patients.

Conclusions

Current evidences emphasize that the temporary implantable nitinol devices are promising alternatives to the standard minimally invasive surgical options for BPH-related LUTS. Further studies are needed to confirm the effectiveness over a long-term follow-up.

Keywords

BPH LUTS iTIND Minimally invasive techniques Nitinol Urethral implantable device 

Notes

Compliance with Ethical Standards

Conflict of Interest

Daniele Amparore, Sabrina De Cillis, Gabriele Volpi, Enrico Checcucci, Matteo Manfredi, Ivano Morra, Michele Di Dio, Cristian Fiori, and Francesco Porpiglia each declares no potential conflicts of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

References

Papers of particular interest, published recently, have been highlighted as: •• Of major importance

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Daniele Amparore
    • 1
  • Sabrina De Cillis
    • 1
  • Gabriele Volpi
    • 1
  • Enrico Checcucci
    • 1
  • Matteo Manfredi
    • 1
  • Ivano Morra
    • 1
  • Michele Di Dio
    • 1
  • Cristian Fiori
    • 1
  • Francesco Porpiglia
    • 1
    Email author
  • on behalf of ESUT Group
  1. 1.Division of Urology, Department Of Oncology, School of Medicine, University of TurinSan Luigi HospitalTurinItaly

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