Current Urology Reports

, 19:95 | Cite as

Management of Overactive Bladder Symptoms After Radical Prostatectomy

  • Benoit PeyronnetEmail author
  • Benjamin M. Brucker
Lower Urinary Tract Symptoms & Voiding Dysfunction (J Sandhu, Section Editor)
Part of the following topical collections:
  1. Topical Collection on Lower Urinary Tract Symptoms & Voiding Dysfunction


Purpose of Review

Post-prostatectomy overactive bladder (OAB) is a common and challenging condition to manage. The aim of the present report was to review the recent evidences regarding OAB symptoms that develop in men after prostatectomy and how to manage them.

Recent Findings

The prevalence of OAB after radical prostatectomy may range from 15.2 to 37.8%. Recent studies have highlighted the role of the urethrogenic mechanism (facilitation of the urethrovesical reflex due to stress urinary incontinence (SUI)) in the genesis of post-prostatectomy OAB in a significant proportion of patients. Several other pathophysiological factors such as iatrogenic decentralization of the bladder, defunctionalized bladder due to severe SUI, detrusor underactivity, or bladder outlet obstruction might be involved. The evaluation should aim to identify the underlying mechanism to tailor the treatment, which could range from SUI surgery, to fixing a urethral stricture, improving bladder emptying or using the conventional spectrum of OAB therapies. There is a paucity of data for OAB therapies specific to post-prostatectomy patients, with the exception of solifenacin, tolterodine, and botulinum toxin. There is currently no data on how preoperative management or surgical technique may prevent post-prostatectomy OAB.


(MeSH) Urinary bladder Overactive Prostatic neoplasms Urinary incontinence Radical prostatectomy 


Compliance with Ethical Standards

Conflicts of Interest

Benoit Peyronnet is a consultant for Allergan, Medtronic, Astellas and Boston Scientific, and an investigator for Ipsen.

Benjamin Brucker is a consultant for Allergan, Watkins Conti, Avadel, Serenity, and an investigator for Ipsen and Medtronic.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.


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© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of UrologyUniversity of RennesRennesFrance
  2. 2.Department of UrologyNew York UniversityNew YorkUSA

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