Current Rheumatology Reports

, 20:54 | Cite as

Current Concepts and Future Directions of Minimally Invasive Treatment for Knee Pain

  • Daryl T. Goldman
  • Rachel Piechowiak
  • Daniel Nissman
  • Sandeep Bagla
  • Ari Isaacson
Imaging (D Mintz, Section Editor)
Part of the following topical collections:
  1. Topical Collection on Imaging


Purpose of Review

The purpose of this paper is to review the percutaneous interventions available for the treatment of osteoarthrosis of the knee that address pain and prolong the time to arthroplasty.

Recent Findings

Corticosteroid injection and viscosupplementation have been the most studied, but there is still no consensus about their value. Thermal nerve ablation, including both radiofrequency ablation and cryoneurolysis, is a promising new modality of therapy that may increase in clinical use given current data showing favorable outcomes. Of the future therapies that are currently under investigation, synovial embolization via the geniculate arteries represents an exciting new approach that may soon be available clinically.


There are various percutaneous interventions available for the treatment of osteoarthrosis of the knee that address pain and prolong the time to arthroplasty.


Osteoarthritis Knee pain Geniculate artery embolization Radiofrequency nerve ablation Thermal ablation Cryotherapy Injectables Corticosteroids Viscosupplementation Platelet-rich plasma PRP Injection Injectable therapies 


Compliance with Ethical Standards

Conflict of Interest

Dr. Isaacson reports personal fees from Cook Medical, Terumo, and Embolx; grants and personal fees from BTG; and grants from Medtronic and Boston Scientific, outside the submitted work. Dr. Bagla reports grants, personal fees, consulting, and research from Boston Scientific and Medtronic, and personal fees and consulting from Terumo, outside the submitted work. Dr. Piechowiak reports grants from Boston Scientific during the conduct of the study. Drs. Goldman and Nissman Parry declare that they have no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.


Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Daryl T. Goldman
    • 1
  • Rachel Piechowiak
    • 2
  • Daniel Nissman
    • 3
  • Sandeep Bagla
    • 2
  • Ari Isaacson
    • 4
  1. 1.Icahn School of Medicine at Mount SinaiNew YorkUSA
  2. 2.Vascular & Interventional RadiologyVascular Institute of VirginiaPrince William CountyUSA
  3. 3.Department of RadiologyUniversity of North Carolina School of MedicineChapel HillUSA
  4. 4.Vascular and Interventional RadiologyUniversity of North Carolina School of MedicineChapel HillUSA

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