Changes in the 8th Edition of the American Joint Committee on Cancer (AJCC) Staging of Head and Neck Cancer: Rationale and Implications
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Purpose of Review
The objectives of this article are to review the major changes in the staging of head and neck cancers and the rationale for the modifications.
Information gathered from various institutional reports lead to a better understanding of the clinical and biological behavior of head and neck tumors, resulting in distinct outcomes, which were used to update the staging system.
This article reviews the changes in the staging of head and neck cancers published in the 8th edition of the AJCC/UICC TNM staging system.
KeywordsTNM staging Head and neck cancer Squamous cell carcinoma Thyroid cancer HPV-related oropharyngeal cancer
This work was funded in part through the NIH/NCI Cancer Center Support Grant P30 CA008748.
Compliance with Ethical Standards
Conflict of Interest
Daniella Karassawa Zanoni, Snehal G. Patel, and Jatin P. Shah declare they have no conflict of interest.
Human and Animal Rights and Informed Consent
This article does not contain any studies with human or animal subjects performed by any of the authors.
Papers of particular interest, published recently, have been highlighted as: • Of importance
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