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Capillary Rarefaction as an Index for the Microvascular Assessment of Hypertensive Patients

  • Areti Triantafyllou
  • Panagiota AnyfantiEmail author
  • Athina Pyrpasopoulou
  • Georgios Triantafyllou
  • Spyros Aslanidis
  • Stella Douma
Mediators, Mechanisms, and Pathways in Tissue Injury (T Fujita, Section Editor)
Part of the following topical collections:
  1. Topical Collection on Mediators, Mechanisms, and Pathways in Tissue Injury

Abstract

Arterial hypertension represents a leading cause of cardiovascular mortality and morbidity worldwide through its detrimental effects on target organs. Therefore, the early identification and appropriate management of high-risk patients emerges as extremely important. Given that the microvasculature is subject to a series of morphological and functional changes under the continuous effect of high blood pressure, research over the last years has gradually moved toward the identification of specific microcirculatory alterations that may serve as early prognostic markers of cardiovascular risk. Dermal capillaries represent an “open window” for the in vivo study of human microcirculation that has been long used mainly for the study of rheumatic diseases. However, capillaroscopy has been relatively understudied and only recently applied in the field of hypertension. Capillaroscopy represents a forthcoming promising estimate of the microvascular status in hypertensive patients, with capillary rarefaction representing the most typical finding. The present review aims at summarizing available evidence and the main findings, as well as the premises and promises, of capillary rarefaction as a tool for evaluating patients with hypertension.

Keywords

Capillaroscopy Hypertension Microvascular alterations Cardiovascular risk 

Notes

Compliance with Ethics Guidelines

Conflict of Interest Areti Triantafyllou, Panagiota Anyfanti, Athina Pyrpasopoulou, Georgios Triantafyllou, Spyros Aslanidis, and Stella Douma declare that they have no conflicts of interest.

Human and Animal Rights and Informed Consent This article does not contain any studies with human or animal subjects performed by any of the authors.

Financial Disclosures None.

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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Areti Triantafyllou
    • 1
  • Panagiota Anyfanti
    • 2
    Email author
  • Athina Pyrpasopoulou
    • 2
  • Georgios Triantafyllou
    • 1
  • Spyros Aslanidis
    • 2
  • Stella Douma
    • 1
  1. 1.3rd Department of Internal Medicine, Papageorgiou HospitalAristotle University of ThessalonikiThessalonikiGreece
  2. 2.2nd Propaedeutic Department of Internal Medicine, Hippokration HospitalAristotle University of ThessalonikiThessalonikiGreece

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