A Review of Telehealth Innovations for HIV Pre-Exposure Prophylaxis (PrEP)

  • Rebecca TougerEmail author
  • Brian R. Wood
The Science of Prevention (JD Stekler and JM Baeten, Section Editors)
Part of the following topical collections:
  1. Topical Collection on The Science of Prevention


Purpose of Review

This review summarizes novel interventions that employ technology to improve HIV pre-exposure prophylaxis (PrEP) availability, uptake, and adherence.

Recent Findings

Several notable technology-based programs are increasing access to PrEP in unique ways. We identified multiple models for using telehealth to bolster PrEP dissemination and adherence, such as mobile applications that offer PrEP prescribing without an in-person visit, longitudinal distance telementoring for community provider PrEP education and clinical guidance, and electronic consults for PrEP specialist support in the primary care setting. Outcomes data for all of these modalities are limited but show promise.


Technology-based interventions can address gaps in the PrEP care continuum. Future research should assess and compare outcomes, scalability, cost-effectiveness, and sustainability. Costs associated with the creation of new technological tools slow innovation and the field would benefit from a platform for technology sharing.


Telehealth HIV prevention Pre-exposure prophylaxis Technology 



The authors would like to thank a number of clinicians, investigators, and telehealth developers who provided valuable information and input on applications described in this manuscript. The authors extend thanks to Dr. Joanne Stekler of the University of Washington, Dr. Lauren Beste at the Veterans Affairs (VA) Puget Sound Medical Center as well as Dr. Marissa Meier and Dr. Melissa Murphy at the VA Portland Healthcare System, Dr. Michael Ohl and Angela Hoth at the University of Iowa, Dr. Jeffrey Klausner and Oliver Refugio at UCLA, Dr. Aaron Siegler at Emory, Jonathan Bandy at PlushCare, and Merissa Hawkins at Nurx. Thanks also to Dr. Colin Lindsay for assistance with table formatting.

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflicts of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.


Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.University of WashingtonSeattleUSA
  2. 2.Division of Allergy and Infectious DiseasesUniversity of WashingtonSeattleUSA

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