Breastfeeding and Type 2 Diabetes: Systematic Review and Meta-Analysis
Purpose of Review
Breastfeeding has short- and long-term benefits for child health. In this systematic review, we updated a review on the association between breastfeeding and type 2 diabetes.
A meta-analysis published in 2015 reported that breastfeeding protects against type 2 diabetes (pooled odds ratio, 0.65 (95% confidence interval, 0.48; 0.86)). In the present update, we identified three recently published studies. An internet-based study reported that at a mean age of 25.6 years, exclusive breastfeeding in the first 6 months protected against type 2 diabetes (odds ratio, 0.63 (95% confidence interval, 0.41; 0.95)). In a retrospective cohort, those subjects who had been breastfed before hospital discharge were less likely of presenting diabetes (odds ratio, 0.83 (95% confidence interval, 0.69; 0.99)). In a case-control study, the odds of type 2 diabetes in adolescents was lower for those exclusively breastfed at hospital discharge (odds ratio, 0.52 (95% confidence interval, 0.36; 0.74)). In the meta-analysis, the pooled odds ratio was 0.67 (95% confidence interval, 0.56; 0.80).
The updated systematic review and meta-analysis suggests that breastfeeding protects from type 2 diabetes.
KeywordsBreastfeeding Human milk Glycemia Type 2 diabetes
Bernardo Lessa Horta has a Scientific Productivity Scholarship (Level 1A) from the Brazilian Research Council (CNPq). This study was financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil (CAPES) - Finance Code 001.
Compliance with Ethical Standards
Conflict of Interest
The authors declare that they have no conflict of interest.
Human and Animal Rights and Informed Consent
This article does not contain any studies with human or animal subjects performed by any of the authors.
Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance
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