Current Cardiology Reports

, 21:129 | Cite as

Is There Currently a Place for Combined Mitral and Aortic Transcatheter Interventions?

  • Rodney De PalmaEmail author
  • Crochan J. O’Sullivan
  • Magnus Settergren
Structural Heart Disease (RJ Siegel and NC Wunderlich, Section Editors)
Part of the following topical collections:
  1. Topical Collection on Structural Heart Disease


Purpose of Review

The goal was to evaluate published data on the incidence, diagnosis, and management of symptomatic combined mitral and aortic valvular disease. Furthermore, to identify the role of treatment using contemporary transcatheter techniques.

Recent Findings

Up to a quarter of symptomatic adult valvular disease is caused by multiple left-sided valvular lesions. The etiologic spectrum of this combined disease has shifted from rheumatic to degenerative. Both presentation and diagnosis of lesions are modified compared with isolated disease. Based upon narrative review, there are only limited observational experiences, insufficient to provide robust guidance. These data, however, indicate the feasibility of interventions such as transcatheter aortic valve replacement and edge-to-edge mitral valve repair to treat such disease and mitigate the risks of open surgery.


Combined aortic and mitral valve disease is commonly encountered. There is a role for transcatheter interventions based on limited data; however, more research is needed.


Multivalve Multiple valve disease Combined valve disease Transcatheter intervention 


Compliance with Ethical Standards

Conflict of Interest

Rodney De Palma, Crochan J. O’Sullivan, and Magnus Settergren declare that they have no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.


Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Rodney De Palma
    • 1
    Email author
  • Crochan J. O’Sullivan
    • 1
  • Magnus Settergren
    • 1
  1. 1.Heart and Vascular ThemeKarolinska University Hospital and Karolinska InstitutetStockholmSweden

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