Current Cardiology Reports

, 21:8 | Cite as

Chagas Cardiomyopathy in Latin America Review

  • Jefferson Luis VieiraEmail author
  • Fábio Rocha Fernandes Távora
  • Maria Gyslane Vasconcelos Sobral
  • Glauber Gean Vasconcelos
  • Germana Porto Linhares Almeida
  • Juliana Rolim Fernandes
  • Laura Leite da Escóssia Marinho
  • Daniel Francisco de Mendonça Trompieri
  • João David De Souza Neto
  • Juan Alberto Cosquillo Mejia
Heart Failure (HJ Eisen, Section Editor)
Part of the following topical collections:
  1. Topical Collection on Heart Failure


Purpose of Review

Chagas cardiomyopathy is a major public health disease in Latin America and, due to migration, is becoming a worldwide health and economic burden. This review sought to present the clinical and epidemiological aspects of Chagas cardiomyopathy, as well as some specific features and principles of treatment. We also retrospectively assessed our institutional experience with mechanical circulatory support in refractory heart failure due to Chagas cardiomyopathy over a 10-year period.

Recent Findings

The role of antiparasitic treatment in patients with heart failure due to Chagas cardiomyopathy is controversial. Heart transplantation, although formerly contraindicated, is currently established as an important therapeutic option. Also, the favorable characteristics of Chagas patients, such as younger age, little comorbidity, and no reoperations or severe pulmonary hypertension, could be an advantage for a mechanical circulatory support indication in advanced heart failure due to Chagas cardiomyopathy.


Despite the absence of large evidence-based data, much has been accomplished since Carlos Chagas’ discovery one century ago. Our institutional experience shows that mechanical circulatory support in Chagas patients is associated with more successful bridging to heart transplantation when compared to non-Chagas patients.


Chagas disease Cardiomyopathy Heart failure Anatomopathology Heart transplantation Mechanical circulatory support 


Compliance with Ethical Standards

Conflict of Interest

Jefferson Luis Vieira, Fábio Rocha Fernandes Távora, Maria Gyslane Vasconcelos Sobral, Glauber Gean Vasconcelos, Germana Porto Linhares Almeida, Juliana Rolim Fernandes, Laura Leite da Escóssia Marinho, Daniel Francisco de Mendonça Trompieri, João David De Souza Neto, and Juan Alberto Cosquillo Mejia declare that they have no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.


Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Jefferson Luis Vieira
    • 1
    Email author
  • Fábio Rocha Fernandes Távora
    • 1
  • Maria Gyslane Vasconcelos Sobral
    • 1
  • Glauber Gean Vasconcelos
    • 1
  • Germana Porto Linhares Almeida
    • 1
  • Juliana Rolim Fernandes
    • 1
  • Laura Leite da Escóssia Marinho
    • 1
  • Daniel Francisco de Mendonça Trompieri
    • 1
  • João David De Souza Neto
    • 1
  • Juan Alberto Cosquillo Mejia
    • 1
  1. 1.Messejana Heart and Lung Hospital Dr. Carlos Alberto Studart GomesFortalezaBrazil

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