Current Cardiology Reports

, 20:81 | Cite as

Heart Transplantation and Mechanical Circulatory Support in Adults with Congenital Heart Disease

  • John D. Serfas
  • Priyesh A. Patel
  • Richard A. KrasuskiEmail author
Congenital Heart Disease (RA Krasuski, Section Editor)
Part of the following topical collections:
  1. Topical Collection on Congenital Heart Disease


Purpose of Review

To assess current management strategies for advanced heart failure in adults with congenital heart disease, including heart transplantation and mechanical circulatory support.

Recent Findings

Current data demonstrate that adults with CHD generally experience higher short-term mortality after heart transplantation and MCS implantation, but enjoy superior long-term survival. Such patients are nonetheless less likely to receive a transplant than non-ACHD peers due to a variety of factors, including lack of applicability of current listing criteria to HF in ACHD. MCS is underutilized in ACHD, but provides similar quality of life benefits for ACHD and non-ACHD patients alike.


Heart failure in ACHD is complex and difficult to treat, and both heart transplantation and mechanical circulatory support are often challenging to implement in this patient population. However, long-term results are encouraging, and existing data supports increasing use of MCS and transplant earlier in their disease course. Multidisciplinary care is critical to success in these complex patients.


Adult congenital heart disease Heart transplantation Mechanical circulatory support LVAD Failing Fontan 


Compliance with Ethical Standards

Conflict of Interest

John D. Serfas, Priyesh Patel, and Richard A. Krasuski declare that they have no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.


Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • John D. Serfas
    • 1
  • Priyesh A. Patel
    • 1
  • Richard A. Krasuski
    • 1
    Email author
  1. 1.Duke University Medical CenterDurhamUSA

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