Evaluation of factors affecting time to achieve dry weight among hemodialysis patients using bioimpedance spectroscopy
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Achieving and maintaining dry weight appears to be an effective strategy for controlling and maintaining normotension among hypertensive patients on hemodialysis (HD).
The present study aimed to determine the time at which the majority of patients achieve postdialysis dry weight using bioimpedance spectroscopy (BIS).
A total of 220 HD patients were prospectively assessed for fluid overload using the Fresenius body composition monitor (BCM). BCM readings were taken at 30 and 45 min postdialysis.
Among the 220 patients included in this study, 120 (54.5%) achieved a euvolemic state at 30 min, and 25 (11.4%) achieved it at 45 min according to the BCM. In the multivariate analysis, vascular access other than arteriovenous fistula (AVF) (OR = 0.286, p value = 0.049) and cardiovascular disease (OR = 0.384, p value = 0.026) had a statistically significant negative association and receiving HD at Hospital Universiti Sains Malaysia (HUSM) (OR = 2.705, p value = 0.008) had a statistically significant positive association with achieving a euvolemic state at 30 min.
This suggests that assessing the hydration status at 45 min postdialysis in all patients or in those with identified risk factors for not achieving a euvolemic state at 30 min will provide a relatively accurate assessment for most patients.
KeywordsBody composition monitor Dry weight Hemodialysis Hypertension
We are thankful to the Institute of Postgraduate Studies (IPS) of Universiti Sains Malaysia (USM) for the fellowship support (ref. no. P-FD0011/15(R)).
Conceived and designed the experiments: AK and AHK. Performed the experiments: AK, AHK, and ASA. Analyzed the data: AK and NA. Contributed reagents/materials/analysis tools: SASS, AK, and SHG. Wrote the paper: AK. Final approval of manuscript: AHK, ASA, and SASS.
Authors have no support or funding for current manuscript.
Compliance with ethical standards
The authors declare that they have no competing interests.
Our study was approved by the Human Resource Ethics Committee of Hospital Universiti Sains Malaysia (USM/JEPeM/16020058). All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
Informed consent was obtained from all individual participants included in the study.
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