Towards Qualification of Additively Manufactured Ti6Al4V (ELI) Medical Implants
- 52 Downloads
In recent years, the production of customized medical implants through additive manufacturing by the Centre for Rapid Prototyping and Manufacturing in South Africa has grown significantly. While satisfactory results have been obtained and the quality of life of many patients has been improved, further research is required to enable the production of qualified components. This paper shares the growing acceptance of additive manufacturing, as well as the establishment of a South African Additive Manufacturing Strategy. An overview of the progress made by the Collaborative Programme in Additive Manufacturing is presented. The scope of the metals research performed towards the qualification of additive manufacturing of Ti6Al4V medical implants is discussed. Examples are given of internationally leading work on utilizing these implants, which were additively manufactured under an ISO 13485 system, in maxillofacial reconstructive surgery. Lastly, the development of an affordable polyurethane artificial heart valve is presented as a different type of medical implant.
This research was supported and funded by the South African Department of Science and Technology through the Collaborative Program in Additive Manufacturing, Contract No.: CSIR-NLC-CPAM-15-MOA-CUT-01. The financial support of the South African Technology Innovation Agency, as well as the South African Research Chairs Initiative of the Department of Science and Technology and the National Research Foundation of South Africa (Grant No 97994), is gratefully acknowledged.
- 1.R. D’Aveni, Harvard Business Review 40 (2015).Google Scholar
- 2.W.B. du Preez and G. Booysen, in Proceedings of the 13th World Conference on Titanium, ed. by V. Venkatesh, A.L. Pilchak, J.E. Allison, S. Ankem, R. Boyer, J. Christodoulou, H.L. Fraser, M.A. Imam, Y. Kosaka, H.J. Rack, A. Chatterjee, and A. Woodfield, TMS (The Minerals, Metals and Materials Society, 2016), pp. 1325–1329, ISBN 978-1-119-29366-8.Google Scholar
- 6.D. de Beer, W. du Preez, H. Greyling (convenor), F. Prinsloo, F. Sciammarella, N. Trollip, M. Vermeulen, with contributions from T. Wohlers, A South African additive manufacturing strategy, Department of Science and Technology (2016), http://www.rapdasa.org/wp-content/uploads/2017/02/South-African-Additive-Manufacturing-Strategy. Accessed 13 July 2018.
- 7.W.B. du Preez, D.J. de Beer, and S. Afr, J. Ind. Eng. 26, 85 (2015).Google Scholar
- 8.K. Thejane, S. Chikosha, W.B. du Preez, and S. Afr, J. Ind. Eng. 28, 161 (2017).Google Scholar
- 9.K. Thejane, Characterisation and monitoring of Ti6Al4V ELI powder used for the qualification of medical implants produced through additive manufacturing, M Eng. dissertation, Central University of Technology, Free State, Bloemfontein, South Africa, 2018.Google Scholar
- 10.ASTM F3001-14, Standard Specification for Additive Manufacturing Titanium-6 Aluminum-4 Vanadium ELI (Extra Low Interstitial) with Powder Bed Fusion (West Conshohocken: ASTM International, 2014).Google Scholar
- 12.L.B. Malefane, W.B. du Preez, M. Maringa, and S. Afr, J. Ind. Eng. 28, 188 (2017).Google Scholar
- 13.L.B. Malefane, W.B. du Preez, M. Maringa, and A. du Plessis, S. Afr. J. Ind. Eng. 29(3), 299 (2018)Google Scholar
- 16.L. Masheane, W.B. du Preez, and J. Combrinck, in Proceedings of the 17th RAPDASA Annual International Conference, VUT Southern Gauteng Science and Technology Park, South Africa (2016), ISBN 978-0-620-72061-8.Google Scholar
- 17.L.R. Masheane, Development of a repeatable dip moulding process for manufacturing polymer artificial heart valves, M.Eng. dissertation, Central University of Technology, Free State, Bloemfontein, South Africa, 2017.Google Scholar
- 18.ISO 5840-2:2015, Cardiovascular implants—Cardiac Valve Prostheses—Part 2: Surgically Implanted Heart Valve Substitutes, ANSI Webstore, https://webstore.ansi.org. Accessed 18 July 2018.