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Influence of reclaimed water discharge on the dissemination and relationships of sulfonamide, sulfonamide resistance genes along the Chaobai River, Beijing

  • Ning Zhang
  • Xiang LiuEmail author
  • Rui Liu
  • Tao Zhang
  • Miao LiEmail author
  • Zhuoran Zhang
  • Zitao Qu
  • Ziting Yuan
  • Hechun Yu
Research Article

Abstract

Reclaimed water represents an important source of antibiotics and antibiotic resistance genes, threatening the ecological safety of receiving environments, while alleviating water resource shortages. This study investigated the dissemination of sulfonamide (SAs), sulfonamide resistance genes (SRGs), and class one integrons (intI1) in the surface water of the recharging area of the Chaobai River. The three antibiotics sulfamethoxazole, trimethoprim, and sulfadiazine had the highest abundance. The highest absolute abundances were 2.91×106, 6.94×106, and 2.18×104 copies/mL for sul1, sul2, and intI1 at the recharge point, respectively. SRGs and intI1 were widespread and had high abundance not only at the recharging point, but also in remote areas up to 8 km away. Seasonal variations of SRGs abundance followed the order of summer>autumn>spring>winter. Significant correlations were found between SRGs and intI1 (R2 = 0.887 and 0.786, p<0.01), indicating the potential risk of SRGs dissemination. Strong correlations between the abundance of SRGs and environmental factors were also found, suggesting that appropriate environmental conditions favor the spread of SRGs. The obtained results indicate that recharging with reclaimed water causes dissemination and enrichment of SAs and SRGs in the receiving river. Further research is required for the risk assessment and scientific management of reclaimed water.

Keywords

Sulfonamide residues Sulfonamide resistance genes Reclaimed water recharge Surface water Class one integrons 

Notes

Acknowledgements

The authors would like to thank the National Natural Science Foundation of China (Grant No. 51378287) for the financial support of this work.

Supplementary material

11783_2019_1099_MOESM1_ESM.pdf (199 kb)
Supplementary material, approximately 200 KB.

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Copyright information

© Higher Education Press and Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  • Ning Zhang
    • 1
    • 2
  • Xiang Liu
    • 1
    Email author
  • Rui Liu
    • 1
  • Tao Zhang
    • 3
  • Miao Li
    • 1
    Email author
  • Zhuoran Zhang
    • 1
  • Zitao Qu
    • 4
  • Ziting Yuan
    • 5
  • Hechun Yu
    • 5
  1. 1.School of EnvironmentTsinghua UniversityBeijingChina
  2. 2.Division of Environment and Resources Research, Transport Planning and Research InstituteMinistry of TransportBeijingChina
  3. 3.Chinese Academy for Environmental PlanningBeijingChina
  4. 4.Institute of Chemistry, Industrial ChemistryTechnical University of Munich (Asian Campus)SingaporeSingapore
  5. 5.School of Water Resources and EnvironmentChina University of Geosciences (Beijing)BeijingChina

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