Journal of Central South University of Technology

, Volume 14, Issue 6, pp 798–802 | Cite as

Synthesis of calixarenes and their extraction performance for ester catechins

  • Yi Jian-min  (易健民)
  • Huang Sai-jin  (黄赛金)
  • Tang Ke-wen  (唐课文)Email author
  • Huang Ke-long  (黄可龙)


A series of extractants (tert-butylcalix[6]arene, tert-butylcalix[8]arene and octeacetate of tert-butylcalix[8]arene) were synthesized, and their structures were identified by IR and 1H-NMR. The distribution behavior of ester catechins monomer in the aqueous and chloroform two-phase system containing one of calixarene was studied. The influences of different extractants, concentration of tert-butylcalix[8]arene and extraction temperature on the partition coefficients and the separation factors were investigated. The experiment results show that tert-butylcalix[8]arene is the best extractant that forms a more stable supramolecular compound with gallocatechin gallate (GCG) than with epigallocathechin gallate (EGCG) or epicatechin gallate (ECG). When the concentration of p-tert-butylcalix[8]arene is 3.79 mmol/L, the extraction temperature is 4 °C, the partition coefficients of KGCG, KECG, KEGCG are 0.987, 0.629, 0.449, the separation factors of a1 and a2 are 1.450 and 1.596, respectively. The important factors influencing the extraction properties of calixarene are discovered to be its cavity size and hydrogen bonding.

Key words

calixarene synthesis ester catechin monomer extraction 


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Copyright information

© Published by: Central South University Press, Sole distributor outside Mainland China: Springer 2007

Authors and Affiliations

  • Yi Jian-min  (易健民)
    • 1
    • 2
  • Huang Sai-jin  (黄赛金)
    • 2
  • Tang Ke-wen  (唐课文)
    • 1
    Email author
  • Huang Ke-long  (黄可龙)
    • 2
  1. 1.Department of Chemistry and Chemical EngineeringHunan Institute of Science and TechnologyYueyangChina
  2. 2.School of Chemistry and Chemical EngineeringCentral South UniversityChangshaChina

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