Two cases of air leak syndrome after bone marrow transplantation successfully treated by the pleural covering technique
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Air leak syndrome (ALS) is a rare complication after bone marrow transplantation (BMT) and usually has a fatal outcome because of the high recurrence rate and treatment-refractory nature. A 32-year-old man with a history of BMT for acute lymphoblastic leukemia suffered from metachronous bilateral ALS. Bullectomy and the pleural covering procedure (PLC) were successfully performed for each side of the thorax. After surgery, no relapse of pneumothorax was seen for 2 years on the right side and for 1 year on the left side. A 38-year-old man with a history of BMT for acute myelogenous leukemia (AML) suffered from ALS at the thorax on the left side. Bullectomy and the PLC were successfully performed. After that no recurrence of left pneumothorax for 7 years. We experienced two cases of ALS after BMT successfully treated by the PLC. This technique may be a viable treatment option for future lung transplantation.
KeywordsAir leak syndrome Bone marrow transplantation Pleural covering procedure
Compliance with ethical standards
Conflict of interest
The authors have no conflicts of interest to declare.
The study protocol was approved by the Ethical Review Board for Clinical Studies at Osaka University (control number 10026-3).
- 7.Kurihara M, Mizobuchi T, Kataoka H, Sato T, Kumasaka T, et al. A Total Pleural Covering for Lymphangioleiomyomatosis Prevents Pneumothorax Recurrence. PLoS One. 2016;11(9).Google Scholar