Internal and Emergency Medicine

, Volume 13, Issue 5, pp 805–809 | Cite as

Changes in global longitudinal strain in renal transplant recipients following 12 months of exercise

  • Minetti Enrico
  • Riggs Klika
  • Chiara Ingletto
  • Gabriele Mascherini
  • Gianni Pedrizzetti
  • Laura StefaniEmail author
Research Letter to the Editor


Renal transplant recipients (RTR) patients are at elevated risk for cardiac dysfunction prior to transplantation due to existing comorbidities such as diabetes, hypertension, and sedentary behavior [1], and are at increased cardiovascular (CV) mortality risk following surgery due to multiple drug therapies, immunosuppression, and further physical inactivity following surgery [2]. As such, early detection of cardiac pathology and monitoring of function is warranted in order to provide safe and appropriate therapy. Among the non-invasive methods to assess myocardial function, echocardiographic strain is increasingly recognized as an effective technique to investigate cardiac performance. Global longitudinal strain (GLS) has been demonstrated to be the most direct, valid and reliable tool for the assessment of left ventricular (LV) function [3], and may also be used to identify sub-clinical LV dysfunction in potential cardiomyopathies [4].

To date, there are no data available...



The authors wish to thank Stefano Pedri–ESAOTE-Italy for his technical support and update of the strain software.


No funding for this manuscript.

Compliance with ethical standards

Conflict of interest

All authors declare that they have no conflict of interest.

Statement of human and animal rights

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.


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Copyright information

© SIMI 2018

Authors and Affiliations

  1. 1.Nephrology UnitUniversity Hospital CareggiFlorenceItaly
  2. 2.Sports Medicine Center, Clinical and Experimental DepartmentUniversity of FlorenceFlorenceItaly
  3. 3.Department of Engineering and ArchitectureUniversity of TriesteTriesteItaly

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