Changes in global longitudinal strain in renal transplant recipients following 12 months of exercise
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Renal transplant recipients (RTR) patients are at elevated risk for cardiac dysfunction prior to transplantation due to existing comorbidities such as diabetes, hypertension, and sedentary behavior , and are at increased cardiovascular (CV) mortality risk following surgery due to multiple drug therapies, immunosuppression, and further physical inactivity following surgery . As such, early detection of cardiac pathology and monitoring of function is warranted in order to provide safe and appropriate therapy. Among the non-invasive methods to assess myocardial function, echocardiographic strain is increasingly recognized as an effective technique to investigate cardiac performance. Global longitudinal strain (GLS) has been demonstrated to be the most direct, valid and reliable tool for the assessment of left ventricular (LV) function , and may also be used to identify sub-clinical LV dysfunction in potential cardiomyopathies .
To date, there are no data available...
The authors wish to thank Stefano Pedri–ESAOTE-Italy for his technical support and update of the strain software.
No funding for this manuscript.
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Conflict of interest
All authors declare that they have no conflict of interest.
Statement of human and animal rights
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
Informed consent was obtained from all individual participants included in the study.
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