In this paper a robotic means of magnetic navigation of an endovascular device a few millimeters in diameter is presented. The technique, based on traditional computer-assisted surgery adapted to intravascular medical procedures, includes a manipulator for magnetic dragging interfaced with an ultrasound system for tracking the endovascular device. The main factors affecting device propulsion are theoretically analyzed, including magnetic forces, fluidic forces, and friction forces between the endovascular device and the vessel. A dedicated set-up for measuring locomotion, and for navigation with and against the flow, has been developed and preliminary tests have been performed to derive the best configuration for controlled magnetic dragging in the vascular system. Experimental outcomes are consistent with a simple analytical model that analyzes dragging of the magnetic capsule in a tube. By means of this model, different working conditions can be considered to select the appropriate conditions, for example flow rate, coefficient of friction, or magnetic properties.
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Naghavi M, Falk E, Hecht HS, Jamieson MJ, Kaul S, Berman D et al (2006) From vulnerable plaque to vulnerable patient-part III: executive summary of the Screening for Heart Attack Prevention and Education (SHAPE) task force report. Am J Cardiol 98(2):2–15
Casscells W, Naghavi M, Willerson JT (2003) Vulnerable atherosclerotic plaque–a multifocal disease. Circulation 107(16):2072–2075
Bourantas CV, Garg S, Naka KK, Thury A, Hoye A, Michalis LK (2011) Focus on the research utility of intravascular ultrasound-comparison with other invasive modalities. Cardiovasc Ultrasoun 9(2):1–10
Chun KRJ, Schmidt B, Köktürk B, Tilz R, Fürnkranz A, Konstantinidou M et al (2008) Catheter ablation-new developments in robotics. Herz 33(8):586–589
SenseiTM Robotic Navigation System (2011) [Online] Available: http://www.hansenmedical.com/sensei. Accessed 7 Sept 2011
CorPath® 200 System (2011) [Online] Available: http://www.corindus.com/products/CorPath200.aspx. Accessed 9 Sept 2011
NiobeTM Remote Controlled Magnetic Navigation System (2011) [Online] Available: http://www.stereotaxis.com/. Accessed 9 Sept 2011
Pan Q, Guo S, Okada T (2010) Development of a wireless hybrid microrobot for biomedical applications. Conf Proc IEEE/RSJ Int Conf Intell Rob Syst 2010:5768–5773
Fountain TWR, Kailat PV, Abbott JJ (2010) Wireless control of magnetic helical microrobots using a rotating-permanent-magnet manipulator. Conf Proc IEEE Rob Aut 2010:576–581
Martel S, Mohammadi M, Lu OZ, Pouponneau P (2009) Flagellated magnetotactic bacteria as controlled MRI-trackable propulsion and steering systems for medical nanorobots operating in the human microvasculature. Int J Robot Res 28(4):571–582
Arcese L, Cherry A, Fruchard M, Ferreira A (2010) Optimal trajectory for a microrobot navigating in blood vessels. Conf Proc IEEE Eng Med Bio Soc 2010:1950–1953
Choi H, Choi J, Jeong S, Yu C, Park JO, Park S (2009) Two-dimensional locomotion of a microrobot with a novel stationary electromagnetic actuation system. Smart Mater Struct 18(11):115017–115023
Yesin KB, Vollmers K, Nelson BJ (2006) Modeling and control of untethered biomicrorobots in a fluidic environment using electromagnetic fields. Int J Robot Res 25(5):527–536
Nelson BJ, Kaliakatsos IK, Abbot JJ (2010) Microrobots for minimally invasive medicine. Annu Rev Biomed Eng 12:55–85
Saam T, Hatsukam TS, Yarnykh VL, Hayes CE, Underhill H, Chu BC et al (2007) Reader and platform reproducibility for quantitative assessment of carotid atherosclerotic plaque using 1.5T Siemens, Philips, and general electric scanners. J Magn Reson Imaging 26(2):344–352
Kerwin WS, O’Brien KD, Ferguson MS, Polissar N, Hatsukami TS, Yuan C (2006) Inflammation in carotid atherosclerotic plaque: a dynamic contrast-enhanced MR imaging study. Radiology 241(2):459–468
Saba L, Caddeo G, Sanfilippo R, Montisci R, Mallarini G (2007) Efficacy and sensitivity of axial scans and different reconstruction methods in the study of the ulcerated carotid plaque using multidetector-row CT angiography: comparison with surgical results. Am J Neuroradiol 28(4):716–723
Whittingham TA (2007) Medical diagnostic applications and sources. Prog Biophys Mol Biol 93(1):84–110
Kakkos SK, Stevens JM, Nicolaides AN, Kyriacou E, Pattichis CS, Geroulakos G et al (2007) Texture analysis of ultrasonic images of symptomatic carotid plaques can identify those plaques associated with ipsilateral embolic brain infarction. Eur J Vasc Endovasc 33(4):422–429
Schick F (2005) Whole-body MRI at high field: technical limits and clinical potential. Eur Radiol 15(5):946–959
Chinzei K, Kikinis R, Jolesz FA (1999) MR compatibility of mechatronic devices: design criteria. Conf Proc Med Image Comput Comput Assist Interv 1999:1020–1030
Xu XC, Hu CH, Sun L, Yen J, Shung KK (2005) High-frequency high frame rate ultrasound imaging system for small animal imaging with linear arrays. Conf Proc IEEE Int Ultrason Symp 2005:1431–1434
Ciuti G, Valdastri P, Menciassi A, Dario P (2010) Robotic magnetic steering and locomotion of capsule endoscope for diagnostic and surgical endoluminal procedures. Robotica 28(2):199–207
White FH (1991) Viscous fluid flow. McGraw-Hill, New York
Simi M, Ciuti G, Tognarelli S, Valdastri P, Menciassi A, Dario P (2010) Magnetic link design for a robotic laparoscopic camera. J Appl Phys 107(9):302–303
Prokopovich P, Perni S (2010) Prediction of the frictional behavior of mammalian tissues against biomaterials. Acta Biomater 6:4052–4059
Takashimaa K, Shimomuraa R, Kitoua T, Teradaa H, Yoshinakab K, Ikeuchia K (2007) Contact and friction between catheter and blood vessel. Tribol Int 40:319–328
Salerno M, Ciuti G, Lucarini G, Rizzo R, Valdastri P, Menciassi A, Landi A, Dario P (2012) A discrete-time localization method for capsule endoscopy based on on-board magnetic sensing. Meas Sci Technol. 23(1). doi:10.1088/0957-0233/23/1/015701
Liu J, Spincemaille P, Codella NCF, Nguyen TD, Prince MR, Wang Y (2010) Respiratory and cardiac self-gated free-breathing cardiac CINE imaging with multiecho 3D hybrid radial SSFP acquisition. Magn Reson Med 63(5):1230–1237
This work was supported by the Fondazione Cassa di Risparmio di Pisa in the framework of the Micro-VAST project (http://www.microvast.it). The authors wish to thank A. Melani and N. Funaro for their help with manufacture of the equipment, and P. Miloro for his help with development of the equipment. We would like thank P. Valdastri for his suggestions and support and G. Lucarini for providing coefficient of friction values.
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Tognarelli, S., Castelli, V., Ciuti, G. et al. Magnetic propulsion and ultrasound tracking of endovascular devices. J Robotic Surg 6, 5–12 (2012) doi:10.1007/s11701-011-0332-1
- Magnetic propulsion
- Ultrasound tracking
- Vascular surgery
- Computer-assisted surgery