Voltammetric sensing of minoxidil using a molecularly imprinted polymer (MIP)-modified carbon paste electrode
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This study presents voltammetric sensing of minoxidil using a molecularly imprinted polymer (MIP). For fabrication of the electrochemical sensor, the synthesized MIP was incorporated into the carbon paste electrode (CPE). MIP-CPE and non-imprinted polymer carbon paste electrode were compared for the recognition ability toward minoxidil. The most important parameters affecting sensor performance were optimized and a calibration curve was then plotted using differential pulse voltammetric technique. Under optimum conditions, the sensor has a linear response in the 1–400 nM minoxidil concentration range and a 0.3 nM limit of detection (at an S/N ratio of 3). Also, the selectivity of the sensor was investigated. Finally, this sensor was applied successfully for minoxidil determination in real samples with different matrices.
KeywordsMolecularly imprinted polymer (MIP) Voltammetric sensing Minoxidil
The authors gratefully acknowledge the support of this work by the Shohadaye Hoveizeh University of Technology Research for financial support.
Compliance with ethical standards
Conflict of interest
The authors declare that there is no conflict of interest with any financial organization regarding the material discussed in the manuscript.
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