Potential of Venlafaxine in the inhibition of mild steel corrosion in HCl: insights from experimental and computational studies

  • Sumayah Bashir
  • Hassane Lgaz
  • III-Min Chung
  • Ashish KumarEmail author
Original Paper


The corrosion-inhibiting behavior and adsorption of Venlafaxine on mild steel has been examined using 1 M HCl at 298 K. Techniques used include weight loss studies, potentiodynamic polarization studies, electron impedance spectroscopy, computational studies (Monte Carlo simulation studies) and AFM studies. The polarization data revealed that Venlafaxine mostly behaves as mixed type of inhibitor. The data from weight loss results suggested that inhibition efficiency varied directly with concentration and inversely with temperature. A quantum chemical calculation and molecular dynamic (MD) simulation studies were used to further validate inhibition mechanism.

Graphical abstract


Mild steel Weight loss Tafel DFT EIS 



  1. Adejoro IA, Ojo FK, Obafemi SK (2015) Corrosion inhibition potentials of ampicillin for mild steel in hydrochloric acid solution. J Taibah Univ Sci 9:196–202. CrossRefGoogle Scholar
  2. Bashir S, Singh G, Kumar A (2017) Shatavari (Asparagus racemosus) as green corrosion inhibitor of aluminium in acidic medium. J Mater Environ Sci 8:4284. Google Scholar
  3. Bashir S, Sharma V, Lgaz H, Chung IM, Singh A, Kumar A (2018a) The inhibition action of analgin on the corrosion of mild steel in acidic medium: a combined theoretical and experimental approach. J Mol Liq 263:454–462. CrossRefGoogle Scholar
  4. Bashir S, Singh G, Kumar A (2018b) An investigation on mitigation of corrosion of aluminium by Origanum vulgare in acidic medium. Protect Metals Phys Chem Surf 54:148–152. CrossRefGoogle Scholar
  5. Benabdellah M, Aouniti A, Dafali A, Hammouti B, Benkaddour M, Yahyi A, Ettouhami A (2006) Investigation of the inhibitive effect of triphenyltin 2-thiophene carboxylate on corrosion of steel in 2 M H3PO4 solutions. Appl Surf Sci 252:8341–8347. CrossRefGoogle Scholar
  6. Bentiss F, Traisnel M, Lagrenee M (2000) The substituted 1, 3, 4-oxadiazoles: a new class of corrosion inhibitors of mild steel in acidic media. Corros Sci 42:127–146. CrossRefGoogle Scholar
  7. Bentiss F, Lebrini M, Lagrenee M (2005a) Thermodynamic characterization of metal dissolution and inhibitor adsorption processes in mild steel/2, 5-bis (n-thienyl)-1, 3, 4-thiadiazoles/hydrochloric acid system. Corros Sci 47:2915–2931. CrossRefGoogle Scholar
  8. Bentiss F, Lebrini M, Lagrenée M (2005b) Thermodynamic characterization of metal dissolution and inhibitor adsorption processes in mild steel/2, 5-bis (n-thienyl)-1, 3, 4-thiadiazoles/hydrochloric acid system. Corros Sci 47:2915–2931. CrossRefGoogle Scholar
  9. Bentiss F, Lebrini M, Lagrenee M (2005c) Thermodynamic characterization of metal dissolution and inhibitor adsorption processes in mild steel/2, 5-bis (n-thienyl)-1, 3, 4-thiadiazoles/hydrochloric acid system. Corros Sci 47:2915–2931. CrossRefGoogle Scholar
  10. Bockris JOM, Reddy AKN, Gamboa-Aldeco M, Gamboa-Aldeco M (2000) Modern electrochemistry 2A. Fundamentals of ElectrodicsGoogle Scholar
  11. Bouklah M, Hammouti B, Lagrenee M, Bentiss F (2006) Thermodynamic properties of 2, 5-bis (4-methoxyphenyl)-1, 3, 4-oxadiazole as a corrosion inhibitor for mild steel in normal sulfuric acid medium. Corros Sci 48:2831–2842. CrossRefGoogle Scholar
  12. da Conceicao TF, Scharnagl N, Dietzel W, Hoeche D, Kainer KU (2011) Study on the interface of PVDF coatings and HF-treated AZ31 magnesium alloy: determination of interfacial interactions and reactions with self-healing properties. Corros Sci 53:712–719. CrossRefGoogle Scholar
  13. Delley B (2000) From molecules to solids with the DMol 3 approach. J Chem Phys. Google Scholar
  14. Delley B (2006) Ground-state enthalpies: evaluation of electronic structure approaches with emphasis on the density functional method. J Phys Chem A 110:13632–13639. CrossRefGoogle Scholar
  15. Eddy NO, Odoemelam SA, Ekwumemgbo P (2009) Inhibition of the corrosion of mild steel in H2SO4 by penicillin G. Sci Res Essays 4:033–038Google Scholar
  16. Elachouri M, Hajji MS, Salem M, Kertit S, Aride J, Coudert R, Essassi E (1996) Some nonionic surfactants as inhibitors of the corrosion of iron in acid chloride solutions. Corrosion 52:103–108. CrossRefGoogle Scholar
  17. Elkadi L, Mernari B, Traisnel M, Bentiss F, Lagrenee M (2000) The inhibition action of 3, 6-bis (2-methoxyphenyl)-1, 2-dihydro-1, 2, 4, 5-tetrazine on the corrosion of mild steel in acidic media. Corros Sci 42:703–719. CrossRefGoogle Scholar
  18. El-Mahdy GA, Mahmoud SS (1995) Inhibition of acid corrosion of pure aluminum with 5-benzylidine-1-methyl-2-methylthio-imidazole-4-one. Corrosion 51:436–440. CrossRefGoogle Scholar
  19. El-Sherbini EF, Wahaab SA, Deyab M (2005) Ethoxylated fatty acids as inhibitors for the corrosion of zinc in acid media. Mater Chem Phys 89:183–191. CrossRefGoogle Scholar
  20. Emregul KC, Hayvali M (2004) Studies on the effect of vanillin and protocatechualdehyde on the corrosion of steel in hydrochloric acid. Mater Chem Phys 83:209–216. CrossRefGoogle Scholar
  21. Flis J, Zakroczymski T (1996) Impedance study of reinforcing steel in simulated pore solution with tannin. J Electrochem Soc 143:2458–2464. CrossRefGoogle Scholar
  22. Gece G (2011) Drugs: a review of promising novel corrosion inhibitors. Corros Sci 53:3873–3898. CrossRefGoogle Scholar
  23. Ghanbari A, Attar MM, Mahdavian M (2010) Corrosion inhibition performance of three imidazole derivatives on mild steel in 1 M phosphoric acid. Mater Chem Phys 124:1205–1209. CrossRefGoogle Scholar
  24. Goel R, Siddiqi WA, Ahmed B, Hussan J (2010) Corrosion inhibition of mild steel in HCl by isolated compounds of Riccinus communis (L.). Journal of Chemistry 7:S319–S329. Google Scholar
  25. Hameed RA, Al-Shafey HI, Abu-Nawwas AH (2014) 2-(2, 6-dichloranilino) phenyl acetic acid drugs as eco-friendly corrosion inhibitors for mild steel in 1 M HCl. Int J Electrochem Sci 9:6006–6019Google Scholar
  26. Hoai NS, Hien PV, Mathesh M, Hanh VT (2019) Improved corrosion resistance of steel in ethanol fuel blend by titania nanoparticles and Aganonerion polymorphum leaf extract. ACS Omega. Google Scholar
  27. James AO, Oforka NC, Abiola OK (2007) Inhibition of acid corrosion of mild steel by pyridoxal and pyridoxol hydrochlorides. Int J Electrochem Sci 2:278–284Google Scholar
  28. Kokalj A (2012) On the HSAB based estimate of charge transfer between adsorbates and metal surfaces. Chem Phys 393:1–12. CrossRefGoogle Scholar
  29. Kumar A, Bashir S (2016) Ethambutol: a new and effective corrosion inhibitor of mildsteel in acidic medium. Russ J Appl Chem 89:1158–1163. CrossRefGoogle Scholar
  30. Kumar SH, Karthikeyan S (2013) Amoxicillin as an efficient green corrosion inhibitor for mild steel in 1 M sulphuric acid. J Mater Environ Sci 4:675–984Google Scholar
  31. Lgaz H, Salghi R, Larouj M, Elfaydy M, Jodeh S, Rouifi Z, Oudda H (2016) Experimental, theoretical and Monte Carlo simulation of quinoline derivative as effective corrosion inhibitor for mild steel in 1 M HCl. J Mater Environ Sci 7:4471–4488. Google Scholar
  32. Lgaz H, Salghi R, Jodeh S, Hammouti B (2017) Effect of clozapine on inhibition of mild steel corrosion in 1.0 M HCl medium. J Mol Liq 225:271–280. CrossRefGoogle Scholar
  33. Li X, Tang L, Li L, Mu G, Liu G (2006) Synergistic inhibition between o-phenanthroline and chloride ion for steel corrosion in sulphuric acid. Corros Sci 48:308–321. CrossRefGoogle Scholar
  34. Loto RT, Loto CA, Ranyaoa M (2012) Pyrimidine derivatives as environmentally-friendly corrosion inhibitors: a review. Int J Phys Sci 7:2697–2705. Google Scholar
  35. Magaji L, Ameh PO, Eddy NO, Uzairu A, Siaka AA, Habib S, Gumel SM (2012) Ciprofloxacin as corrosion inhibitors for mild steel-effects of concentration and temperature. Int J Modern Chem 2:64–73Google Scholar
  36. Megalai MS, Ramesh R, Maniula P (2013) Inhibition of corrosion mild steel in acid media by trazodone drug. Res Desk 2:326–333Google Scholar
  37. Oguzie EE (2007) Corrosion inhibition of aluminium in acidic and alkaline media by Sansevieria trifasciata extract. Corros Sci 49:1527–1539. CrossRefGoogle Scholar
  38. Materials Studio, Revision 6.0, Accelrys Inc., San Diego, USA, 2013.
  39. Sharma V, Kumar S, Bashir S, Ghelichkhah Z, Obot IB, Kumar A (2018) Use of Sapindus (reetha) as corrosion inhibitor of aluminium in acidic medium. Mater Res Express 5:076510. CrossRefGoogle Scholar
  40. Shriver DF, Atkins PW, Langford CH (1994) Inorganic Chemistry. Oxford University Press, OxfordGoogle Scholar
  41. Sigirik G, Tuken T, Erbil M (2015) Inhibition efficiency of aminobenzonitrile compounds on steel surface. Appl Surf Sci 324:232–239. CrossRefGoogle Scholar
  42. Singh A, Singh AK, Quraishi MA (2010) Dapsone: a novel corrosion inhibitor for mild steel in acid media. Open Electrochem J 2:43–51CrossRefGoogle Scholar
  43. Singh A, Pramanik T, Kumar A, Gupta M (2013) Phenobarbital: a new and effective corrosion inhibitor for mild steel in 1 M HCl solution. Asian J Chem 25:17. Google Scholar
  44. Solmaz R, Kardaş G, Culha M, Yazıcı B, Erbil M (2008) Investigation of adsorption and inhibitive effect of 2-mercaptothiazoline on corrosion of mild steel in hydrochloric acid media. Electrochim Acta 53:5941–5952. CrossRefGoogle Scholar
  45. Trabanelli G (1991) Whitney award lecture: inhibitors—an old remedy for a new challenge. Corrosion 47:410–419. CrossRefGoogle Scholar
  46. Tsuru T, Haruyama S, Gijutsu B (1978) Corrosion inhibition of iron by amphoteric surfactants in 2 M HCl. J Jpn Soc Corros Eng 27:573–581. Google Scholar
  47. Vracar LM, Drazic DM (2002) Adsorption and corrosion inhibitive properties of some organic molecules on iron electrode in sulfuric acid. Corros Sci 44:1669–1680. CrossRefGoogle Scholar
  48. Wahdan MH, Hermas AA, Morad MS (2002) Corrosion inhibition of carbon-steels by propargyltriphenylphosphonium bromide in H2SO4 solution. Mater Chem Phys 76:111–118. CrossRefGoogle Scholar
  49. Zhang Q, Hua Y (2010) Corrosion inhibition of aluminum in hydrochloric acid solution by alkylimidazolium ionic liquids. Mater Chem Phys 119:57–64. CrossRefGoogle Scholar
  50. Zhao T, Mu G (1999) The adsorption and corrosion inhibition of anion surfactants on aluminium surface in hydrochloric acid. Corros Sci 41:1937–1944. CrossRefGoogle Scholar

Copyright information

© Institute of Chemistry, Slovak Academy of Sciences 2019

Authors and Affiliations

  1. 1.Department of Chemistry, Faculty of Technology and SciencesLovely Professional UniversityPhagwaraIndia
  2. 2.Department of Crop Science, College of Sanghur Life ScienceKonkuk UniversitySeoulSouth Korea

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