Laparoscopic Sleeve Gastrectomy in Sickle Cell Disease: a Case Series

  • Jin Han
  • Michel Gowhari
  • Victor R. Gordeuk
  • Santosh L. SarafEmail author
Brief Communication


With improved care, the number of sickle cell patients with obesity is increasing. The experience with bariatric surgery in this patient population is limited. We describe four adult patients with mild sickling genotypes who underwent laparoscopic sleeve gastrectomy. The patients achieved marked weight loss with percentage of excess weight loss ranging from 56 to 68%. The surgery was associated with decreases in white blood cell counts and lower random glucose concentrations. No short-term or long-term complications related to the surgery were observed. Our report supports bariatric surgery as a feasible weight-loss option in this patient population.


Sickle cell disease Bariatric surgery Glucose White blood cell 


Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.

Ethical Approval Statement

This study was reviewed and granted exempt status by UIC Institutional Review Board. As this is a retrospective study, for this kind of study, formal consent is not required.

Informed Consent

Does not apply to this retrospective study.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Pharmacy Practice, College of PharmacyUniversity of Illinois at ChicagoChicagoUSA
  2. 2.Comprehensive Sickle Cell Center, Section of Hematology/Oncology, Department of MedicineUniversity of Illinois at ChicagoChicagoUSA
  3. 3.Center for Pharmacoepidemiology and Pharmacoeconomic ResearchUniversity of Illinois at ChicagoChicagoUSA

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